Childhood pustular psoriasis associated with Panton-Valentine leukocidin-producing Staphylococcus aureus

被引:15
作者
Pouessel, Guillaume
Ythier, Hubert
Carpentier, Olivier
Vachee, Anne
Etienne, Jerome
Catteau, Benoit
机构
[1] Hop Victor Provo, Serv Pediat, Dept Pediat, F-59100 Roubaix, France
[2] Hop Victor Provo, Dept Dermatol, Roubaix, France
[3] Hop Victor Provo, Bacteriol Lab, Roubaix, France
[4] INSERM, French Reference Ctr Staphylococci, E0230, F-69008 Lyon, France
[5] Fac Med, Lyon, France
[6] Lille Univ Hosp, Dept Dermatol, Lille, France
[7] Fac Med, Lille, France
关键词
D O I
10.1111/j.1525-1470.2007.00459.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report the association of a generalized pustular psoriasis and infection by Staphylococcus aureus which produced Panton-Valentine leukocidin in a 5-year-old child. Another S. aureus strain with the same toxin gene content was also isolated among three family members presenting with cutaneous lesions. Although a methicillin-resistant staphylococcal strain has been reported in association with pustular psoriasis, this is the first report of a Panton-Valentine leukocidin strain associated with generalized pustular psoriasis. The causal relationship between S. aureus produced Panton-Valentine leukocidin and skin lesions is discussed.
引用
收藏
页码:401 / 404
页数:4
相关论文
共 21 条
[11]   Juvenile generalized pustular psoriasis [J].
Kalla, G ;
Goyal, AM .
PEDIATRIC DERMATOLOGY, 1996, 13 (01) :45-46
[12]  
Karamfilov T, 1998, ACTA DERM-VENEREOL, V78, P220
[13]   A clone of methicillin-resistant Staphylococcus aureus among professional football players [J].
Kazakova, SV ;
Hageman, JC ;
Matava, M ;
Srinivasan, A ;
Phelan, L ;
Garfinkel, B ;
Boo, T ;
McAllister, S ;
Anderson, J ;
Jensen, B ;
Dodson, D ;
Lonsway, D ;
McDougal, LK ;
Arduino, M ;
Fraser, VJ ;
Killgore, G ;
Tenover, FC ;
Cody, S ;
Jernigan, DB .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (05) :468-475
[14]  
Leung DYM, 1998, BRIT J DERMATOL, V139, P17
[15]   Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia [J].
Lina, G ;
Piémont, Y ;
Godail-Gamot, F ;
Bes, M ;
Peter, MO ;
Gauduchon, V ;
Vandenesch, F ;
Etienne, J .
CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1128-1132
[16]   Intrafamilial spread of highly virulent Staphylococcus aureus strains carrying the gene for Panton-Valentine leukocidin [J].
Österlund, A ;
Kahlmeter, G ;
Bieber, L ;
Runehagen, A ;
Breider, JM .
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2002, 34 (10) :763-764
[17]   EPIDEMIOLOGIC DATA ON STAPHYLOCOCCUS-AUREUS STRAINS PRODUCING SYNERGOHYMENOTROPIC TOXINS [J].
PREVOST, G ;
COUPPIE, P ;
PREVOST, P ;
GAYET, S ;
PETIAU, P ;
CRIBIER, B ;
MONTEIL, H ;
PIEMONT, Y .
JOURNAL OF MEDICAL MICROBIOLOGY, 1995, 42 (04) :237-245
[18]   Superantigen production by Staphylococcus aureus in psoriasis [J].
Sayama, K ;
Midorikawa, K ;
Hanakawa, Y ;
Sugai, M ;
Hashimoto, K .
DERMATOLOGY, 1998, 196 (02) :194-198
[19]   The keratinocyte as a target for staphylococcal bacterial toxins [J].
Travers, JB ;
Norris, DA ;
Leung, DYM .
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, 2001, 6 (03) :225-230
[20]  
von Zumbusch LR, 1910, ARCH DERMATOL SYPH-G, V99, P335