Childhood pustular psoriasis associated with Panton-Valentine leukocidin-producing Staphylococcus aureus

被引：15

作者：

Pouessel, Guillaume

Ythier, Hubert

Carpentier, Olivier

Vachee, Anne

Etienne, Jerome

Catteau, Benoit

机构：

[1] Hop Victor Provo, Serv Pediat, Dept Pediat, F-59100 Roubaix, France

[2] Hop Victor Provo, Dept Dermatol, Roubaix, France

[3] Hop Victor Provo, Bacteriol Lab, Roubaix, France

[4] INSERM, French Reference Ctr Staphylococci, E0230, F-69008 Lyon, France

[5] Fac Med, Lyon, France

[6] Lille Univ Hosp, Dept Dermatol, Lille, France

[7] Fac Med, Lille, France

来源：

PEDIATRIC DERMATOLOGY | 2007年 / 24卷 / 04期

关键词：

D O I：

10.1111/j.1525-1470.2007.00459.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report the association of a generalized pustular psoriasis and infection by Staphylococcus aureus which produced Panton-Valentine leukocidin in a 5-year-old child. Another S. aureus strain with the same toxin gene content was also isolated among three family members presenting with cutaneous lesions. Although a methicillin-resistant staphylococcal strain has been reported in association with pustular psoriasis, this is the first report of a Panton-Valentine leukocidin strain associated with generalized pustular psoriasis. The causal relationship between S. aureus produced Panton-Valentine leukocidin and skin lesions is discussed.

引用

页码：401 / 404

页数：4

共 21 条

[1] Peptidoglycan and peptidoglycan-specific ThI cells in psoriatic skin lesions [J].