Spectroscopic Investigation on the Toxic Interaction of Melamine with Herring Sperm DNA

被引:13
作者
Sun, Yajing [1 ]
Liu, Rutao [1 ]
Chi, Zhenxing [1 ]
Qin, Pengfei [1 ]
Fang, Xiaoyan [1 ]
Mou, Yue [1 ]
机构
[1] Shandong Univ, Sch Environm Sci & Engn, Jinan 250100, Peoples R China
关键词
DNA; Melamine; Toxic Interaction; BOVINE SERUM-ALBUMIN; CALF THYMUS DNA; FORMALDEHYDE RESINS; FLUORESCENCE PROBE; METHYLENE-BLUE; MECHANISM; COMPLEXES; BINDING; CANCER; ACID;
D O I
10.1002/jbt.20341
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The toxic interaction of melamine with herring sperm DNA (hs-DNA) was investigated by using fluorescence and UV-vis absorption spectra techniques. The experimental results showed that the toxic interaction between melamine and hs-DNA occurred. Fluorescence quenching experiments indicated the existence of electrostatic binding between melamine and hs-DNA. The binding constants K-A and the binding site numbers were calculated by means of the Stern Volmer equation and were 9.8 x 10(4) L mol(-1) and 1.3, respectively. Both the results of fluorescence spectra and UV vis absorption spectra verified that there are electrostatic binding between melamine and hs-DNA. The possibility in the presence of a classical intercalation binding mode could be ruled out by using DNA unwinding experiments. (C) 2010 Wiley Periodicals, Inc. J Biochem Mol Toxicol 24:323-329, 2010; View this article online at wileyonlinelibrary.com. DOI 10:1002/jbt.20341
引用
收藏
页码:323 / 329
页数:7
相关论文
共 50 条
[21]   Interaction between tryptophan-vanillin Schiff base and herring sperm DNA [J].
Zhang, Yan ;
Wang, Xingming ;
Ding, Lisheng .
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2010, 75 (09) :1191-1201
[22]   Systematical synthesis of distamycin analogues and their interaction with herring sperm DNA [J].
Tang, FL ;
Wang, J ;
Liu, D ;
Li, JJ ;
Yuan, G .
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2002, 49 (06) :1073-1077
[23]   Exploring the binding interaction between herring sperm DNA and sunitinib: insights from spectroscopic and molecular docking approaches [J].
Shi, Jie-Hua ;
Pan, Dong-Qi ;
Zhou, Kai-Li ;
Lou, Yan-Yue .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2019, 37 (04) :837-845
[24]   Electrochemical and spectroscopic studies of the interaction between the neuroleptic drug, gabapentin, and DNA [J].
Jalali, Fahimeh ;
Dorraji, Parisa S. .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2012, 70 :598-601
[25]   Study on the electrochemical and spectroscopic characteristics of holmium ion and its interaction with DNA [J].
Tilehkan, Ali ;
Arvand, Majid .
SCIENTIFIC REPORTS, 2024, 14 (01)
[26]   Electrochemical Investigation of DNA Interaction with Melamine and its Related Compounds (MARCs) [J].
Shen, Hao-Yu ;
Zheng, Hui-Min ;
Zhu, Ning ;
Liu, Yang-Qing ;
Gao, Jing ;
Li, Jia .
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2010, 5 (11) :1587-1596
[27]   Interaction of Schiff base rare earth complexes with herring sperm DNA [J].
Li X.-F. ;
Feng X.-Q. ;
Yang S. ;
Zhu Y.-C. .
Faguang Xuebao, 7 (873-880) :873-880
[28]   Spectroscopy studies of interaction between methylene blue and herring sperm DNA [J].
Fei Dan ;
Wang Xing-Ming ;
Li Hong-Bo ;
Ding Li-Sheng ;
Hu Ya-Min ;
Zhang Huan ;
Zhao Shi-Lin .
ACTA CHIMICA SINICA, 2008, 66 (04) :443-448
[29]   Study on the Interaction of Formononetin and Herring Sperm DNA by Electrochemical Methods and Spectroscopy [J].
Sun, Li ;
Wang, Xueliang ;
Zou, Na ;
Li, Hongying ;
Yu, Zhangyu .
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2015, 10 (09) :7349-7360
[30]   Interaction between melamine and bovine serum albumin: Spectroscopic approach and density functional theory [J].
Yan, Hua ;
Wu, Junyong ;
Dai, Guoliang ;
Zhong, Aiguo ;
Yang, Jianguo ;
Liang, Huading ;
Pan, Fuyou .
JOURNAL OF MOLECULAR STRUCTURE, 2010, 967 (1-3) :61-64