Steroidal glycosides from the underground parts of Agapanthus inapertus and their cytotoxic activity

被引：0

作者：

Yokosuka, Akihito ^{[1
]}

Mimaki, Yoshihiro ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Lab Med Pharmacognosy, Sch Pharm, Tokyo 1920392, Japan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2007年 / 2卷 / 01期

关键词：

Agapanthus inapertus; Liliaceae; spirostanol glycoside; cytotoxic activity; HL-60; cells;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Phytochemical investigation of the underground parts of Agapanthus inapertus (Liliaceae) has resulted in the isolation of three new spirostanol glycosides (1, 3, and 4), along with a known spirostanol glycoside (2) and two known spirostanols (5 and 6). The structures of the new glycosides were determined by spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds were evaluated for their cytotoxic activity against H.L-60 human promyelocytic leukemia cells.

引用

页码：35 / 39

页数：5

共 8 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].