Post-transplant lymphoproliferative disease in tonsils of children with liver transplantation

被引：11
作者：
De Diego, JI
Prim, MP
Hardisson, D
Verdaguer, JM
Jara, P
机构：
[1] Autonomous Univ Madrid, Hosp La Paz, Dept Otorhinolaryngol, E-28049 Madrid, Spain
[2] Autonomous Univ Madrid, Hosp La Paz, Dept Pediat Hepatol, E-28049 Madrid, Spain
来源：
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 2001年 / 58卷 / 02期
关键词：
lymphoproliferative disease; tonsillectomy; liver transplant;
D O I：
10.1016/S0165-5876(01)00415-3
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Objective: To assess the incidence and characteristics of post-transplant lymphoproliferative disease (PTLD) in tonsils of the liver transplanted children. Methods: All patients under 14 years of age recipients of a liver transplant at the institution and operated on for tonsillectomy under suspicion of malignancy were included in this study. Results: Seven patients underwent surgery on their tonsils under suspicion of PTLD. One case of B-cell lymphoma. and three cases of polymorphic diffuse B-cell hyperplasia were found. This represents an incidence of 1.4% of PTLD in the tonsils of the 283 pediatric liver transplants performed at the hospital. Conclusion: The incidence of PTLD in tonsils after liver transplantation is very low at the institution. However. it is very important to follow-up allograft recipients for early diagnosis of this entity. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：113 / 118
页数：6
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