Prevalence of vitamin D deficiency, insufficiency and secondary hyperparathyroidism in the elderly inpatients and living in the community of the city of Sao Paulo, Brazil

被引:57
作者
Saraiva, Gabriela Lupomi [1 ]
Cendoroglo, Maysa Seabra [2 ]
Ramos, Luiz Roberto [2 ]
Quirino Araujo, Lara Miguel [2 ]
Vieira, Jose Gilberto H. [1 ]
Maeda, Sergio Setsuo [1 ]
Borba, Victoria Z. C. [3 ]
Kunii, Ilda [1 ]
Hayashi, Lillian F. [1 ]
Lazaretti-Castro, Marise [1 ]
机构
[1] Univ Fed Sao Paulo, Dept Endocrinol, Escola Paulista Med, BR-04034970 Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Geriatr, Escola Paulista Med, BR-04034970 Sao Paulo, Brazil
[3] Univ Fed Parana, Serv Endocrinol, BR-80060000 Curitiba, Parana, Brazil
基金
巴西圣保罗研究基金会;
关键词
vitamin D; secondary hyperparathyroidism; elderly; deficiency; insufficiency; 25-hydroxivitamin D; epidemiology; BONE-MINERAL DENSITY; 2-YEAR FOLLOW-UP; POSTMENOPAUSAL WOMEN; D SUPPLEMENTATION; QUANTITATIVE ULTRASOUND; PARATHYROID-HORMONE; HYPOVITAMINOSIS D; CALCIUM; OLDER; FRACTURES;
D O I
10.1590/S0004-27302007000300012
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The occurrence of osteoporotic fractures in the elderly is associated with reduced levels of vitamin D and resulting secondary hyperparathyroidism, and inpatients are the ones at a higher risk. In Brazil, given its high level of insolation, the population's large amount of vitamin D is inferred to be adequate. In this study we aimed to assess the serum levels of 25-hydroxivitamin D (25OHD), parathormone (PTH) and ionized calcium (Cai), as well as to analyze the prevalence of both hypovitaminosis D and secondary hyperparathyroidism in the elderly living in the city of Sao Paulo. We studied 177 inpatients (125 women and 52 men) with mean age (SD) 76.6 (9.0) years, and 243 outpatients (168 women and 75 men) aged 79.1 (5.9) years. In this assessment 71.2% in the inpatients group and 43.8% in the outpatients group had 25OHD levels below the minimum recommended (50 nmol/l), with the women presenting with levels considerably lower than the men. Secondary hyperparathyroidism occurred in 61.7% of the inpatients and in 54% of the outpatients. Considering the results achieved, we recommend vitamin D supplementation in effective doses for the Brazilian elderly population, in addition to suggesting a discussion for the implementation of vitamin D-enhanced food policies, particularly oriented to the ones at a greater risk.
引用
收藏
页码:437 / 442
页数:6
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