Mitochondrial fission in apoptosis

被引:647
作者
Youle, RJ [1 ]
Karbowski, M [1 ]
机构
[1] Natl Inst Neurol Disorders & Stroke, Biochem Sect, Surg Neurol Branch, Natl Inst Hlth, Bethesda, MD 20892 USA
关键词
D O I
10.1038/nrm1697
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.
引用
收藏
页码:657 / 663
页数:7
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