Synthesis of α-hydroxy phosphonates using a solid supported base

被引：18

作者：

Alexander, CW ^{[1
]}

Albiniak, PA ^{[1
]}

Gibson, LR ^{[1
]}

机构：

[1] Coll Charleston, Dept Chem & Biochem, Charleston, SC 29424 USA

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2000年 / 167卷

基金：

美国国家科学基金会;

关键词：

alpha-hydroxy phosphonate; ion exchange resin; quaternary ammonium hydroxide; diethyl phosphite;

D O I：

10.1080/10426500008082399

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A mild, efficient synthesis of alpha -hydroxy phosphonates is described where a quaternary ammonium hydroxide ion exchange resin is used as a base to promote the addition of diethyl phosphite to aryl aldehydes for a Pudikov type reaction.

引用

页码：205 / 209

页数：5

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