SPRINT Revisited: Updated Results and Implications

被引：17

作者：

Wright, Jackson T. ^{[1
]}

Whelton, Paul K. ^{[3
]}

Johnson, Karen C. ^{[4
]}

Snyder, Joni K. ^{[5
]}

Reboussin, David M. ^{[6
]}

Cushman, William C. ^{[4
]}

Williamson, Jeff D. ^{[7
]}

Pajewski, Nicholas M. ^{[6
]}

Cheung, Alfred K. ^{[9
,10
]}

Lewis, Cora E. ^{[11
]}

Oparil, Suzanne ^{[12
]}

Rocco, Michael, V ^{[8
]}

Beddhu, Srinivasan ^{[9
,10
]}

Fine, Lawrence J. ^{[5
]}

Cutler, Jeffrey A. ^{[5
]}

Ambrosius, Walter T. ^{[6
]}

Rahman, Mahboob ^{[1
]}

Still, Carolyn H. ^{[2
]}

Chen, Zhengyi ^{[13
]}

Tatsuoka, Curtis ^{[13
]}

机构：

[1] Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Div Nephrol & Hypertens, 11100 Euclid Ave,Wearn BI,Suite 352, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA

[3] Tulane Univ, Dept Epidemiol, Sch Publ Hlth & Trop Med, New Orleans, LA 70118 USA

[4] Univ Tennessee, Ctr Hlth Sci, Dept Prevent Med, Memphis, TN 38163 USA

[5] NHLBI, Clin Applicat & Prevent Branch, Bldg 10, Bethesda, MD 20892 USA

[6] Wake Forest Sch Med, Dept Biostat & Data Sci, Winston Salem, NC 27101 USA

[7] Wake Forest Sch Med, Sect Gerontol & Geriatr Med, Winston Salem, NC 27101 USA

[8] Wake Forest Sch Med, Sect Nephrol, Winston Salem, NC 27101 USA

[9] Vet Affairs Salt & Ake City Healthcare Syst, Renal Sect, Salt Lake City, UT USA

[10] Univ Utah, Div Nephrol & Hypertens, Salt Lake City, UT USA

[11] Univ Alabama Birmingham, Dept Epidemiol, Birmingham, AL USA

[12] Univ Alabama Birmingham, Dept Med, Birmingham, AL USA

[13] Case Western Reserve Univ, Sch Med, Dept Populat & Quantitat Hlth Sci, Cleveland, OH USA

来源：

HYPERTENSION | 2021年 / 78卷 / 06期

基金：

美国国家卫生研究院;

关键词：

blood pressure; cardiovascular disease; controlled clinical trial; heart failure; hypertension; myocardial infarction; SYSTOLIC BLOOD-PRESSURE; HIGH-RISK PATIENTS; CARDIOVASCULAR OUTCOMES; TREATMENT TARGETS; DECISION-MAKING; KIDNEY-DISEASE; OLDER PATIENTS; HEART-FAILURE; HYPERTENSION; TRIAL;

D O I：

10.1161/HYPERTENSIONAHA.121.17682

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The SPRINT (Systolic Blood Pressure Intervention Trial) results have influenced clinical practice but have also generated discussion regarding the validity, generalizability, and importance of the findings. Following the SPRINT primary results manuscript in 2015, additional results and analyses of the data have addressed these concerns. The primary objective of this article is to respond to key questions that have been raised.

引用

页码：1701 / 1710

页数：10

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