Recent Advances in Diagnostic and Therapeutic Approaches for Breast Can- cer: A Comprehensive Review

被引:41
|
作者
Noor, Fatima [1 ]
Noor, Ayesha [2 ]
Ishaq, Ali Raza [3 ]
Farzeen, Iqra [2 ]
Saleem, Muhammad Hamzah [3 ]
Ghaffar, Kanwal [2 ]
Aslam, Muhammad Farhan [4 ]
Aslam, Sidra [1 ]
Chen, Jen-Tsung [5 ]
机构
[1] Govt Coll Univ, Dept Bioinformat & Biotechnol, Allama Iqbal Rd, Faisalabad 38000, Pakistan
[2] Govt Coll Univ, Dept Zool, Allama Iqbal Rd, Faisalabad 38000, Pakistan
[3] Hubei Univ, Coll Life Sci, Environm Microbial Technol Ctr Hubei Prov, State Key Lab Biocatalysis & Enzyme Engn, Wuhan 430062, Peoples R China
[4] Huazhong Agr Univ, Coll Plant Sci & Technol, MOA Key Lab Crop Ecophysiol & Farming Syst Middle, Wuhan 430070, Peoples R China
[5] Natl Univ Kaohsiung, Dept Life Sci, Kaohsiung 811, Taiwan
关键词
Breast cancer; omics; genes; diagnosis; biomarkers; therapy; LONG NONCODING RNA; CANCER STEM-CELLS; NANOPARTICLES MEDIATED CODELIVERY; IRON-OXIDE NANOPARTICLES; PHOTODYNAMIC THERAPY; GOLD NANOPARTICLES; SILVER NANOPARTICLES; MOLECULAR DOCKING; GENE-THERAPY; IN-VITRO;
D O I
10.2174/1381612827666210303141416
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Breast cancer has been described as the most prevalent lifethreatening cancer in women. Worldwide, breast cancer causes more than 50,000 deaths annually, accounting for 18% of all women deaths [1-4]. A recent publication has estimated that approximately 80% of women diagnosed with breast cancer each year are aged > 45. In the USA, the health burden of breast cancer is increasing at a drastic rate, with 232,240 newly diagnosed patients and A silent monster, breast cancer, is a challenging medical task for researchers. Breast cancer is a lead-ing cause of death in women with respect to other cancers. A case of breast cancer is diagnosed among women every 19 seconds, and every 74 seconds, a woman dies of breast cancer somewhere in the world. Several risk factors, such as genetic and environmental factors, favor breast cancer development. This review tends to pro-vide deep insights regarding the genetics of breast cancer along with multiple diagnostic and therapeutic ap-proaches as problem-solving negotiators to prevent the progression of breast cancer. This assembled data main-ly aims to discuss omics-based approaches to provide enthralling diagnostic biomarkers and emerging novel therapies to combat breast cancer. This review article intends to pave a new path for the discovery of effective treatment options.
引用
收藏
页码:2344 / 2365
页数:22
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