Convenient synthesis of novel heteroatom-substituted quinolines via Friedlander annulation using phosphotungstic acid as a reusable catalyst

被引：3

作者：

Chen, Meng-Meng ^{[1
]}

Zhang, Min ^{[1
]}

Xie, Feng ^{[1
]}

Wang, Xiao-Ting ^{[1
]}

机构：

[1] Jiangnan Univ, Sch Chem & Mat Engn, Wuxi 214122, Peoples R China

来源：

MONATSHEFTE FUR CHEMIE | 2015年 / 146卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Phosphotungstic acid; Heteroatom substituent containing quinolines; Friedlander annulation; SOLVENT-FREE SYNTHESIS; POLYSUBSTITUTED QUINOLINES; HIGHLY EFFICIENT; OXIDATION; ANALOGS; ACCESS; SERIES;

D O I：

10.1007/s00706-014-1358-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Using phosphotungstic acid as a reusable catalyst, a convenient synthesis of novel heteroatom-substituted quinolines from 2-aminoaryl ketones and alpha-heteroatom bearing ketones has been demonstrated via Friedlander annulation. The transformation has the advantages of operational simplicity, wide substrate scope, solvent-free conditions, and catalyst recyclability, making it a practical protocol for the preparation of heteroatom-substituted quinoline products.

引用

页码：663 / 671

页数：9

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