WELL-POSEDNESS AND STABILITY ANALYSIS FOR A MOVING BOUNDARY PROBLEM MODELLING THE GROWTH OF NONNECROTIC TUMORS

被引:11
|
作者
Escher, Joachim [1 ]
Matioc, Anca-Voichita [1 ]
机构
[1] Leibniz Univ Hannover, Inst Appl Math, D-30167 Hannover, Germany
来源
DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B | 2011年 / 15卷 / 03期
关键词
Tumor growth; Moving boundary problem; Well-posedness; Stability; CLASSICAL-SOLUTIONS; BIFURCATION; SPACES;
D O I
10.3934/dcdsb.2011.15.573
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
We study a moving boundary problem describing the growth of nonnecrotic tumors in different regimes of vascularisation. This model consists of two decoupled Dirichlet problem, one for the rate at which nutrient is added to the tumor domain and one for the pressure inside the tumor. These variables are coupled by a relation which describes the dynamic of the boundary. By re-expressing the problem as an abstract evolution equation, we prove local well-posedness in the small Holder spaces context. Further on, we use the principle of linearised stability to characterise the stability properties of the unique radially symmetric equilibrium of the problem.
引用
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页码:573 / 596
页数:24
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