Small-molecule binding at the Src SH2 domain

被引：0
|
作者：
Edwards, P [1 ]
机构：
[1] Pfizer Global Res & Dev, Lead Discovery Technol, Sandwich, Kent, England
来源：
DRUG DISCOVERY TODAY | 2001年 / 6卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：54 / 55
页数：2
相关论文
共 50 条
  • [1] BINDING OF THE SRC SH2 DOMAIN TO PHOSPHOPEPTIDES IS DETERMINED BY RESIDUES IN BOTH THE SH2 DOMAIN AND THE PHOSPHOPEPTIDES
    BIBBINS, KB
    BOEUF, H
    VARMUS, HE
    MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (12) : 7278 - 7287
  • [2] Discovery of novel de novo designed synthetic, small-molecule, nonpeptide ligands that bind to the Src homology (SH2) domain
    Para, KS
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 46 - ORGN
  • [3] Solid-phase binding assays of peptides using EGFP-Src SH2 domain fusion protein and biotinylated Src SH2 domain
    Ye, GF
    Ayrapetov, M
    Nam, NH
    Sun, GQ
    Parang, K
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (22) : 4994 - 4997
  • [4] Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain
    Stover, DR
    Furet, P
    Lydon, NB
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (21) : 12481 - 12487
  • [5] A photoactivatable Src homology 2 (SH2) domain
    Song, X.
    Shang, X.
    Ju, T.
    Cerny, R.
    Niu, W.
    Guo, J.
    RSC ADVANCES, 2016, 6 (56): : 51120 - 51124
  • [6] Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein
    Deprez, P
    Mandine, E
    Gofflo, D
    Meunier, S
    Lesuisse, D
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (09) : 1295 - 1298
  • [7] Structural and thermodynamic analysis of the peptide binding specificity of the SH2 domain of Src kinase
    Lubman, OY
    Waksman, G
    BIOPHYSICAL JOURNAL, 2002, 82 (01) : 330A - 330A
  • [8] Profiling of hematopoietic malignancies by Src Homology 2 (SH2) domain binding pattern.
    Machida, K
    Nollau, P
    Thompson, CM
    Lin, B
    Anderson, KC
    Patel, N
    Mayer, BJ
    BLOOD, 2002, 100 (11) : 603A - 603A
  • [9] Role of electrostatic interactions in SH2 domain recognition: Salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase
    Grucza, RA
    Bradshaw, JM
    Mitaxov, V
    Waksman, G
    BIOCHEMISTRY, 2000, 39 (33) : 10072 - 10081
  • [10] Insights from the energetics binding at the domain-ligand of the Src SH2 domain of water interface
    De Fabritiis, Gianni
    Geroult, Sebastien
    Coveney, Peter V.
    Waksman, Gabriel
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2008, 72 (04) : 1290 - 1297
12345