Rapid and Convenient Synthesis of Original 5-Substituted Quinolino[3,4-b]quinoxalin-6(5H)-ones under Eco-Friendly Conditions

被引：5

作者：

Khoumeri, Omar ^{[1
]}

Vanelle, Francois-Xavier ^{[1
]}

Crozet, Maxime D. ^{[1
]}

Terme, Thierry ^{[1
]}

Vanelle, Patrice ^{[1
]}

机构：

[1] Aix Marseille Univ, UMR CNRS 7273, Fac Pharm, Lab Pharmacochim Radicalaire,ICR, 27 Blvd Jean Moulin CS 30064, F-13385 Marseille 05, France

来源：

SYNLETT | 2016年 / 27卷 / 10期

关键词：

quinoxaline; aromatic anilines; Buchwald-Hartwig reaction; lactamization reaction; QUINOXALINE ANTIBIOTICS; CATALYZED CYCLIZATION; N-HETEROCYCLES; POT SYNTHESIS; DERIVATIVES; INHIBITORS; DISCOVERY; 1,4-DIOXIDE;

D O I：

10.1055/s-0035-1561577

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report herein the synthesis of 5-(substituted)quinolino[3,4-b]quinoxalin-6(5H)-one derivatives from ethyl 3-(2-bromophenyl)quinoxaline-2-carboxylate under one-pot Buchwald-Hartwig coupling-lactamization reaction.

引用

页码：1547 / 1550

页数：4

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