Rapid and Convenient Synthesis of Original 5-Substituted Quinolino[3,4-b]quinoxalin-6(5H)-ones under Eco-Friendly Conditions

被引：5
|
作者：
Khoumeri, Omar [1 ]
Vanelle, Francois-Xavier [1 ]
Crozet, Maxime D. [1 ]
Terme, Thierry [1 ]
Vanelle, Patrice [1 ]
机构：
[1] Aix Marseille Univ, UMR CNRS 7273, Fac Pharm, Lab Pharmacochim Radicalaire,ICR, 27 Blvd Jean Moulin CS 30064, F-13385 Marseille 05, France
来源：
SYNLETT | 2016年 / 27卷 / 10期
关键词：
quinoxaline; aromatic anilines; Buchwald-Hartwig reaction; lactamization reaction; QUINOXALINE ANTIBIOTICS; CATALYZED CYCLIZATION; N-HETEROCYCLES; POT SYNTHESIS; DERIVATIVES; INHIBITORS; DISCOVERY; 1,4-DIOXIDE;
D O I：
10.1055/s-0035-1561577
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report herein the synthesis of 5-(substituted)quinolino[3,4-b]quinoxalin-6(5H)-one derivatives from ethyl 3-(2-bromophenyl)quinoxaline-2-carboxylate under one-pot Buchwald-Hartwig coupling-lactamization reaction.
引用
收藏
页码：1547 / 1550
页数：4
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