Expeditious synthesis of pyrano[2,3,4-de]quinolines via Rh(III)-catalyzed cascade C-H activation/annulation/lactonization of quinolin-4-ol with alkynes

被引：54

作者：

Liao, Gang ^{[1
]}

Song, Hong ^{[1
]}

Yin, Xue-Song ^{[1
,2
]}

Shi, Bing-Feng ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

[2] Wuyi Univ, Sch Chem & Environm Engn, Jiangmen 529020, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 55期

关键词：

ONE-POT SYNTHESIS; CATALYZED OXIDATIVE ANNULATION; N BOND FORMATION; INTERNAL ALKYNES; EFFICIENT SYNTHESIS; ACTIVATION ACCESS; CLEAVAGE; DERIVATIVES; FUNCTIONALIZATION; MULTIPLE;

D O I：

10.1039/c7cc04113f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rh(III)-catalyzed cascade C-H activation/annulation/lactonization of quinoline-4-ols and alkynes has been reported. A broad range of tetracyclic pyrano[2,3,4-de] quinolines have been prepared in one-step with good functional group tolerance, excellent site selectivity, and high efficiency.

引用

页码：7824 / 7827

页数：4

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