Carbamazepine overdose recognized by a tricyclic antidepressant assay

被引:10
作者
Fleischman, A
Chiang, VW
机构
[1] Harvard Univ, Childrens Hosp, Sch Med, Dept Pediat, Boston, MA 02115 USA
[2] Harvard Univ, Childrens Hosp, Sch Med, Div Emergency Med, Boston, MA 02115 USA
关键词
coma; carbamazepine; tricyclic antidepressants;
D O I
10.1542/peds.107.1.176
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Altered mental status in an adolescent presents a diagnostic challenge, and the clinician depends on clinical evaluation and laboratory studies to determine therapy and prognosis. We report the case of adolescent with altered consciousness caused by carbamazepine overdose with a positive tricyclic antidepressant level to alert clinicians to the cross-reactivity of carbamazepine with a toxicology screen for tricyclic antidepressants.
引用
收藏
页码:176 / 178
页数:3
相关论文
共 9 条
[1]  
*ABB LAB, 1995, ABB TDX ASS MAN, P4
[2]   CARDIOVASCULAR EFFECTS OF CARBAMAZEPINE TOXICITY [J].
APFELBAUM, JD ;
CARAVATI, EM ;
KERNS, WP ;
BOSSART, PJ ;
LARSEN, G .
ANNALS OF EMERGENCY MEDICINE, 1995, 25 (05) :631-635
[3]   Carbamazepine interference with an immune assay for tricyclic antidepressants in plasma [J].
Chattergoon, DS ;
Verjee, Z ;
Anderson, M ;
Johnson, D ;
McGuigan, MA ;
Koren, G ;
Ito, S .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1998, 36 (1-2) :109-113
[4]   A FATAL OVERDOSE OF CARBAMAZEPINE - CASE-REPORT AND REVIEW OF LITERATURE [J].
FISHER, RS ;
CYSYK, B .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1988, 26 (07) :477-486
[5]   Serial electrocardiogram changes in acute tricyclic antidepressant overdoses [J].
Liebelt, EL ;
Ulrich, A ;
Francis, PD ;
Woolf, A .
CRITICAL CARE MEDICINE, 1997, 25 (10) :1721-1726
[6]   SIGNS AND SYMPTOMS OF CARBAMAZEPINE OVERDOSE [J].
SCHMIDT, S ;
SCHMITZBUHL, M .
JOURNAL OF NEUROLOGY, 1995, 242 (03) :169-173
[7]   CARBAMAZEPINE OVERDOSE - FEATURES OF 33 CASES [J].
SEYMOUR, JF .
DRUG SAFETY, 1993, 8 (01) :81-88
[8]  
Shannon M, 1998, PEDIATR EMERG CARE, V14, P372
[9]   PEDIATRIC CARBAMAZEPINE INTOXICATION [J].
STREMSKI, ES ;
BRADY, WB ;
PRASAD, K ;
HENNES, HA .
ANNALS OF EMERGENCY MEDICINE, 1995, 25 (05) :624-630