G Protein-Coupled Receptor Kinases: From Molecules to Diseases

被引:1
作者
Gurevich, Eugenia V. [1 ]
Premont, Richard T. [2 ]
Gainetdinov, Raul R. [3 ,4 ,5 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37232 USA
[2] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[3] Italian Inst Technol, Genoa, Italy
[4] Skolkovo Inst Sci & Technol, Skolkovo, Moscow Region, Russia
[5] St Petersburg State Univ, Fac Biol, St Petersburg 199034, Russia
关键词
PHOSPHORYLATION; BETA; DESENSITIZATION; RHODOPSIN; COMPLEX;
D O I
10.1096/fj.14-263657ufm
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:361 / 364
页数:4
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共 12 条
  • [1] LIGHT-DEPENDENT PHOSPHORYLATION OF RHODOPSIN BY BETA-ADRENERGIC-RECEPTOR KINASE
    BENOVIC, JL
    MAYOR, F
    SOMERS, RL
    CARON, MG
    LEFKOWITZ, RJ
    [J]. NATURE, 1986, 321 (6073) : 869 - 872
  • [2] Molecular basis for activation of G protein-coupled receptor kinases
    Boguth, Cassandra A.
    Singh, Puja
    Huang, Chih-chin
    Tesmer, John J. G.
    [J]. EMBO JOURNAL, 2010, 29 (19) : 3249 - 3259
  • [3] Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis
    Dhami, Gurpreet K.
    Ferguson, Stephen S. G.
    [J]. PHARMACOLOGY & THERAPEUTICS, 2006, 111 (01) : 260 - 271
  • [4] Phosphorylation of the platelet-derived growth factor receptor-β and epidermal growth factor receptor by G protein-coupled receptor kinase-2 -: Mechanisms for selectivity of desensitization
    Freedman, NJ
    Kim, LK
    Murray, JP
    Exum, ST
    Brian, L
    Wu, JH
    Peppel, K
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (50) : 48261 - 48269
  • [5] G protein-coupled receptor kinases: More than just kinases and not only for GPCRs
    Gurevich, Eugenia V.
    Tesmer, John J. G.
    Mushegian, Arcady
    Gurevich, Vsevolod V.
    [J]. PHARMACOLOGY & THERAPEUTICS, 2012, 133 (01) : 40 - 69
  • [6] Keeping G proteins at bay:: A complex between G protein-coupled receptor kinase 2 and Gβγ
    Lodowski, DT
    Pitcher, JA
    Capel, WD
    Lefkowitz, RJ
    Tesmer, JJG
    [J]. SCIENCE, 2003, 300 (5623) : 1256 - 1262
  • [7] Multiple Scaffolding Functions of β-Arrestins in the Degradation of G Protein-coupled Receptor Kinase 2
    Nogues, Laura
    Salcedo, Alicia
    Mayor, Federico, Jr.
    Penela, Petronila
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (02) : 1165 - 1173
  • [8] Nonenzymatic Rapid Control of GIRK Channel Function by a G Protein-Coupled Receptor Kinase
    Raveh, Adi
    Cooper, Ayelet
    Guy-David, Liora
    Reuveny, Eitan
    [J]. CELL, 2010, 143 (05) : 750 - 760
  • [9] Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2
    Salcedo, Alicia
    Mayor, Federico, Jr.
    Penela, Petronila
    [J]. EMBO JOURNAL, 2006, 25 (20) : 4752 - 4762
  • [10] Snapshot of activated G proteins at the membrane:: The Gαq-GRK2-Gβγ complex
    Tesmer, VM
    Kawano, T
    Shankaranarayanan, A
    Kozasa, T
    Tesmer, JJG
    [J]. SCIENCE, 2005, 310 (5754) : 1686 - 1690