G Protein-Coupled Receptor Kinases: From Molecules to Diseases

被引：1
作者：
Gurevich, Eugenia V. [1 ]
Premont, Richard T. [2 ]
Gainetdinov, Raul R. [3 ,4 ,5 ]
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37232 USA
[2] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[3] Italian Inst Technol, Genoa, Italy
[4] Skolkovo Inst Sci & Technol, Skolkovo, Moscow Region, Russia
[5] St Petersburg State Univ, Fac Biol, St Petersburg 199034, Russia
来源：
FASEB JOURNAL | 2015年 / 29卷 / 02期
关键词：
PHOSPHORYLATION; BETA; DESENSITIZATION; RHODOPSIN; COMPLEX;
D O I：
10.1096/fj.14-263657ufm
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：361 / 364
页数：4
相关论文
共 12 条
[1]   LIGHT-DEPENDENT PHOSPHORYLATION OF RHODOPSIN BY BETA-ADRENERGIC-RECEPTOR KINASE [J].
BENOVIC, JL ;
MAYOR, F ;
SOMERS, RL ;
CARON, MG ;
LEFKOWITZ, RJ .
NATURE, 1986, 321 (6073) :869-872
[2]   Molecular basis for activation of G protein-coupled receptor kinases [J].
Boguth, Cassandra A. ;
Singh, Puja ;
Huang, Chih-chin ;
Tesmer, John J. G. .
EMBO JOURNAL, 2010, 29 (19) :3249-3259
[3]   Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis [J].
Dhami, Gurpreet K. ;
Ferguson, Stephen S. G. .
PHARMACOLOGY & THERAPEUTICS, 2006, 111 (01) :260-271
[4]   Phosphorylation of the platelet-derived growth factor receptor-β and epidermal growth factor receptor by G protein-coupled receptor kinase-2 -: Mechanisms for selectivity of desensitization [J].
Freedman, NJ ;
Kim, LK ;
Murray, JP ;
Exum, ST ;
Brian, L ;
Wu, JH ;
Peppel, K .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (50) :48261-48269
[5]   G protein-coupled receptor kinases: More than just kinases and not only for GPCRs [J].
Gurevich, Eugenia V. ;
Tesmer, John J. G. ;
Mushegian, Arcady ;
Gurevich, Vsevolod V. .
PHARMACOLOGY & THERAPEUTICS, 2012, 133 (01) :40-69
[6]   Keeping G proteins at bay:: A complex between G protein-coupled receptor kinase 2 and Gβγ [J].
Lodowski, DT ;
Pitcher, JA ;
Capel, WD ;
Lefkowitz, RJ ;
Tesmer, JJG .
SCIENCE, 2003, 300 (5623) :1256-1262
[7]   Multiple Scaffolding Functions of β-Arrestins in the Degradation of G Protein-coupled Receptor Kinase 2 [J].
Nogues, Laura ;
Salcedo, Alicia ;
Mayor, Federico, Jr. ;
Penela, Petronila .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (02) :1165-1173
[8]   Nonenzymatic Rapid Control of GIRK Channel Function by a G Protein-Coupled Receptor Kinase [J].
Raveh, Adi ;
Cooper, Ayelet ;
Guy-David, Liora ;
Reuveny, Eitan .
CELL, 2010, 143 (05) :750-760
[9]   Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2 [J].
Salcedo, Alicia ;
Mayor, Federico, Jr. ;
Penela, Petronila .
EMBO JOURNAL, 2006, 25 (20) :4752-4762
[10]   Snapshot of activated G proteins at the membrane:: The Gαq-GRK2-Gβγ complex [J].
Tesmer, VM ;
Kawano, T ;
Shankaranarayanan, A ;
Kozasa, T ;
Tesmer, JJG .
SCIENCE, 2005, 310 (5754) :1686-1690
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