Imatinib for Pulmonary Arterial Hypertension - Wonder Drug or Killer Drug?

被引：5
作者：
Olschewski, Horst [1 ]
机构：
[1] Med Univ Graz, AT-8036 Graz, Austria
来源：
RESPIRATION | 2015年 / 89卷 / 06期
关键词：
GROWTH-FACTOR EXPRESSION; THERAPY;
D O I：
10.1159/000430997
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页码：513 / 514
页数：2
相关论文
共 11 条
  • [1] Role of platelet-derived growth factor in vascular remodeling during pulmonary hypertension in the ovine fetus
    Balasubramaniam, V
    Le Cras, TD
    Ivy, DD
    Grover, TR
    Kinsella, JP
    Abman, SH
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2003, 284 (05) : L826 - L833
  • [2] Translation of the Philadelphia chromosome into therapy for CML
    Druker, Brian J.
    [J]. BLOOD, 2008, 112 (13) : 4808 - 4817
  • [3] Imatinib for the treatment of pulmonary arterial hypertension
    Ghofrani, HA
    Seeger, W
    Grimminger, F
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) : 1412 - 1413
  • [4] Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy
    Ghofrani, Hossein A.
    Morrell, Nicholas W.
    Hoeper, Marius M.
    Olschewski, Horst
    Peacock, Andrew J.
    Barst, Robyn J.
    Shapiro, Shelley
    Golpon, Heiko
    Toshner, Mark
    Grimminger, Friedrich
    Pascoe, Steve
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 182 (09) : 1171 - 1177
  • [5] Use of Imatinib in Patients with Pulmonary Arterial Hypertension Joint Statement of the "Group Pulmonary Hypertension" of the German Society for Pneumology and the "Working Group Pulmonary Hypertension (AG25)" of the German Society of Cardiology (DGK)
    Hoeper, M. M.
    Opitz, C.
    Olschewski, H.
    Ulrich, S.
    Speich, R.
    Behr, J.
    Halank, M.
    Wilkens, H.
    Klose, H.
    Lange, T. J.
    Gruenig, E.
    Seeger, W.
    Ewert, R.
    Borst, M. M.
    Welte, T.
    Rosenkranz, S.
    Ghofrani, H. Ardeschir
    [J]. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2014, 139 : S151 - S154
  • [6] Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial Hypertension Results of the Randomized IMPRES Study
    Hoeper, Marius M.
    Barst, Robyn J.
    Bourge, Robert C.
    Feldman, Jeremy
    Frost, Adaani E.
    Galie, Nazzareno
    Angel Gomez-Sanchez, Miguel
    Grimminger, Friedrich
    Gruenig, Ekkehard
    Hassoun, Paul M.
    Morrell, Nicholas W.
    Peacock, Andrew J.
    Satoh, Toru
    Simonneau, Gerald
    Tapson, Victor F.
    Torres, Fernando
    Lawrence, David
    Quinn, Deborah A.
    Ghofrani, Hossein-Ardeschir
    [J]. CIRCULATION, 2013, 127 (10) : 1128 - +
  • [7] Humbert M, 1998, EUR RESPIR J, V11, P554
  • [8] Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension
    Perros, Frederic
    Montani, David
    Dorfmueller, Peter
    Durand-Gasselin, Ingrid
    Tcherakian, Colas
    Le Pavec, Jerome
    Mazmanian, Michel
    Fadel, Elie
    Mussot, Sacha
    Mercier, Olaf
    Herve, Philippe
    Emilie, Dominique
    Eddahibi, Saadia
    Simonneau, Gerald
    Souza, Rogerio
    Humbert, Marc
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 178 (01) : 81 - 88
  • [9] Reversal of experimental pulmonary hypertension by PDGF inhibition
    Schermuly, RT
    Dony, E
    Ghofrani, HA
    Pullamsetti, S
    Savai, R
    Roth, M
    Sydykov, A
    Lai, YJ
    Weissmann, N
    Seeger, W
    Grimminger, F
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (10) : 2811 - 2821
  • [10] Efficacy and Safety of Long-Term Imatinib Therapy for Pulmonary Arterial Hypertension
    Speich, Rudolf
    Ulrich, Silvia
    Domenighetti, Guido
    Huber, Lars C.
    Fischler, Manuel
    Treder, Ursula
    Breitenste, Alexander
    [J]. RESPIRATION, 2015, 89 (06) : 515 - 524
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