Microbiology - Metagenomics

被引:274
作者
Hugenholtz, Philip [1 ]
Tyson, Gene W. [2 ]
机构
[1] DOE Joint Genome Inst, Microbial Ecol Program, Walnut Creek, CA 94598 USA
[2] MIT, Dept Civil & Environm Engn, Cambridge, MA 02139 USA
关键词
D O I
10.1038/455481a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Ten years after the term metagenomics was coined, the approach continues to gather momentum. This culture-independent, molecular way of analysing environmental samples of cohabiting microbial populations has opened up fresh perspectives on microbiology.
引用
收藏
页码:481 / 483
页数:3
相关论文
共 6 条
[1]   Community genomics among stratified microbial assemblages in the ocean's interior [J].
DeLong, EF ;
Preston, CM ;
Mincer, T ;
Rich, V ;
Hallam, SJ ;
Frigaard, NU ;
Martinez, A ;
Sullivan, MB ;
Edwards, R ;
Brito, BR ;
Chisholm, SW ;
Karl, DM .
SCIENCE, 2006, 311 (5760) :496-503
[2]   Viral metagenomics [J].
Edwards, RA ;
Rohwer, F .
NATURE REVIEWS MICROBIOLOGY, 2005, 3 (06) :504-510
[3]   An obesity-associated gut microbiome with increased capacity for energy harvest [J].
Turnbaugh, Peter J. ;
Ley, Ruth E. ;
Mahowald, Michael A. ;
Magrini, Vincent ;
Mardis, Elaine R. ;
Gordon, Jeffrey I. .
NATURE, 2006, 444 (7122) :1027-1031
[4]   Community structure and metabolism through reconstruction of microbial genomes from the environment [J].
Tyson, GW ;
Chapman, J ;
Hugenholtz, P ;
Allen, EE ;
Ram, RJ ;
Richardson, PM ;
Solovyev, VV ;
Rubin, EM ;
Rokhsar, DS ;
Banfield, JF .
NATURE, 2004, 428 (6978) :37-43
[5]   Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite [J].
Warnecke, Falk ;
Luginbuehl, Peter ;
Ivanova, Natalia ;
Ghassemian, Majid ;
Richardson, Toby H. ;
Stege, Justin T. ;
Cayouette, Michelle ;
McHardy, Alice C. ;
Djordjevic, Gordana ;
Aboushadi, Nahla ;
Sorek, Rotem ;
Tringe, Susannah G. ;
Podar, Mircea ;
Martin, Hector Garcia ;
Kunin, Victor ;
Dalevi, Daniel ;
Madejska, Julita ;
Kirton, Edward ;
Platt, Darren ;
Szeto, Ernest ;
Salamov, Asaf ;
Barry, Kerrie ;
Mikhailova, Natalia ;
Kyrpides, Nikos C. ;
Matson, Eric G. ;
Ottesen, Elizabeth A. ;
Zhang, Xinning ;
Hernandez, Myriam ;
Murillo, Catalina ;
Acosta, Luis G. ;
Rigoutsos, Isidore ;
Tamayo, Giselle ;
Green, Brian D. ;
Chang, Cathy ;
Rubin, Edward M. ;
Mathur, Eric J. ;
Robertson, Dan E. ;
Hugenholtz, Philip ;
Leadbetter, Jared R. .
NATURE, 2007, 450 (7169) :560-U17
[6]   The Sorcerer II Global Ocean Sampling expedition:: Expanding the universe of protein families [J].
Yooseph, Shibu ;
Sutton, Granger ;
Rusch, Douglas B. ;
Halpern, Aaron L. ;
Williamson, Shannon J. ;
Remington, Karin ;
Eisen, Jonathan A. ;
Heidelberg, Karla B. ;
Manning, Gerard ;
Li, Weizhong ;
Jaroszewski, Lukasz ;
Cieplak, Piotr ;
Miller, Christopher S. ;
Li, Huiying ;
Mashiyama, Susan T. ;
Joachimiak, Marcin P. ;
van Belle, Christopher ;
Chandonia, John-Marc ;
Soergel, David A. ;
Zhai, Yufeng ;
Natarajan, Kannan ;
Lee, Shaun ;
Raphael, Benjamin J. ;
Bafna, Vineet ;
Friedman, Robert ;
Brenner, Steven E. ;
Godzik, Adam ;
Eisenberg, David ;
Dixon, Jack E. ;
Taylor, Susan S. ;
Strausberg, Robert L. ;
Frazier, Marvin ;
Venter, J. Craig .
PLOS BIOLOGY, 2007, 5 (03) :432-466