Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

被引：29

作者：

Guo, Sha-Sha ^{[1
,2
]}

Wang, Zhen-Guo ^{[1
,2
]}

机构：

[1] Shandong Univ Tradit Chinese Med, Key Lab Theory TCM, Minist Educ China, Jinan, Peoples R China

[2] Shandong Univ Tradit Chinese Med, Inst Tradit Chinese Med Literature & Culture, Jinan, Peoples R China

来源：

FRONTIERS IN PHARMACOLOGY | 2022年 / 13卷

关键词：

TCM; traditional Chinese medicine; salvianolic acid B; anticancer activity; apoptosis; mechanism; SQUAMOUS-CELL CARCINOMA; GASTRIC-CANCER; LUNG-CANCER; IN-VITRO; HEAD; MECHANISMS; BIOMARKERS; APOPTOSIS; GROWTH; IMMUNOTHERAPY;

D O I：

10.3389/fphar.2022.1042745

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review summarizes the anticancer activity of Sal-B. Sal-B inhibits tumor growth and metastasis by targeting multiple cell signaling pathways. This review aims to review experimental studies to describe the possible anticancer mechanisms of Sal-B and confirm its potential as a therapeutic drug.

引用

页数：10

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