Secretin family (Class B) G protein-coupled receptors - from molecular to clinical perspectives

被引:15
作者
Poyner, David R. [2 ]
Hay, Debbie L. [1 ]
机构
[1] Univ Auckland, Sch Biol Sci, Auckland 1, New Zealand
[2] Aston Univ, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England
关键词
G protein-coupled receptor; GPCR; family B; secretin; CGRP; CRYSTAL-STRUCTURE; EXTRACELLULAR DOMAIN; PARATHYROID-HORMONE; CGRP RECEPTOR; NMR STRUCTURE; IDENTIFICATION; PHARMACOLOGY; RECOGNITION; ACTIVATION; MECHANISMS;
D O I
10.1111/j.1476-5381.2011.01810.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Family B G protein-coupled receptors represent an important but under-researched group of receptors. This edition of the British Journal of Pharmacology considers the roles and pharmacology of a number of these receptors. Whilst common themes emerge, it is clear that more work is needed to understand the details of each receptor in order to properly exploit them therapeutically.
引用
收藏
页码:1 / 3
页数:3
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