Diffusion-weighted imaging in the prostate: an apparent diffusion coefficient comparison of half-Fourier acquisition single-shot turbo spin-echo and echo planar imaging
Prostate cancer detection using diffusion-weighted imaging is highly affected by the accuracy of the apparent diffusion coefficient (ADC) values in an image. Echo planar imaging (EPI) is a fast sequence commonly used for diffusion imaging but has inherent magnetic susceptibility and chemical shift artefacts associated. A diffusion sequence that is less affected by these artefacts is therefore advantageous. The half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequence was chosen. The diffusion sequences were compared in image quality, repeatability of the ADC value and the effect on the ADC value with varied h values. Eight volunteers underwent three scans of each sequence, on a 1.5-T Siemens system, using b values of 0, 150, 300, 450, 600, 750, 900 and 1000 s/mm(2). ADC maps were created to address the reproducibility of the ADC value when using two b values compared to eight b values. The ADC value using all h values with the HASTE sequence gave the best performance in all tested categories. Both sequences gave significantly different ADC mean values for two b values compared to when using eight b values (P<.05) suggesting larger error is present when using two h values. HASTE was shown to be an improvement over EPI in terms of repeatability, signal variation within a region of interest and standard deviation over the volunteer set. The improved accuracy of the ADC value in the HASTE sequence makes it potentially a more sensitive tumor detection technique. (C) 2012 Elsevier Inc. All rights reserved.
机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
Gibbs, P
;
Pickles, MD
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机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
Pickles, MD
;
Turnbull, LW
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机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
机构:
Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, EnglandHull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England
Gibbs, Peter
;
Pickles, Martin D.
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机构:Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England
Pickles, Martin D.
;
Turnbull, Lindsay W.
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机构:Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England
机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
Gibbs, P
;
Pickles, MD
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
Pickles, MD
;
Turnbull, LW
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, EnglandUniv Hull, Postgrad Med Sch, Div Canc, Ctr MR Investigat, Kingston Upon Hull HU6 7RX, N Humberside, England
机构:
Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, EnglandHull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England
Gibbs, Peter
;
Pickles, Martin D.
论文数: 0引用数: 0
h-index: 0
机构:Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England
Pickles, Martin D.
;
Turnbull, Lindsay W.
论文数: 0引用数: 0
h-index: 0
机构:Hull Royal Infirm, Ctr MR Invest, Kingston Upon Hull HU3 2JZ, N Humberside, England