The aims that indicated in "The Guidance Outline on Elementary and Middle Schools Information Technology Curriculum" are to enable students to have abilities of acquiring, transmitting, processing and applying information through learning information technology courses; cultivate them to have good information literacy; make information technology as a significant way of supporting for lifelong and cooperative learning, laying a necessary foundation of adapting to the study, work and life in information society. With the application of multimedia computers and networks, education and teaching have undergone profound changes that the integration of information technology and subject teaching (or course) has become the focus in educational reform, so how to integrate instruction with the information technology curriculum? I think the idea that combing with other subjects teaching in the information technology curriculum to carry out thematic inquiry learning not only can achieve unique effects, but also is a win-win teaching model of information technology and other teaching courses. This paper aims at exploring the positive ways and meaning of the integration of information technology and other subjects through thematic inquiry learning cases.