The many roles of an RNA editor

被引：195
作者：
Keegan, LP [1 ]
Gallo, A [1 ]
O'Connell, MA [1 ]
机构：
[1] Western Gen Hosp, Human Genet Unit, MRC, Edinburgh EH4 2XU, Midlothian, Scotland
来源：
NATURE REVIEWS GENETICS | 2001年 / 2卷 / 11期
关键词：
D O I：
10.1038/35098584
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The availability of complete genome sequences has made it clear that gene number is not the sole determinant of the complexity of the proteome. Additional complexity that is not readily detected by genome analysis is present in the number and types of RNA transcript that can be derived from each locus. Although alternative splicing is a well-recognized method of generating diversity, the more subtle mechanism of RNA editing is less familiar.
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页码：869 / 878
页数：10
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