A comprehensive review on phytochemicals for fatty liver: are they potential adjuvants?

被引：6

作者：

do Moinho, Tais Menezes ^{[1
]}

Matos, Sandro Leao ^{[1
]}

Carvalho, Carla R. O. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508000 Sao Paulo, Brazil

来源：

JOURNAL OF MOLECULAR MEDICINE-JMM | 2022年 / 100卷 / 03期

基金：

巴西圣保罗研究基金会;

关键词：

Fatty liver; NAFLD; Phytochemicals; Traditional medicine; Metabolic syndrome; ACTIVATED PROTEIN-KINASE; GINKGO-BILOBA EXTRACT; KOREAN RED GINSENG; FACTOR-KAPPA-B; INSULIN-RESISTANCE; HEPATIC STEATOSIS; UNCARIA-TOMENTOSA; OXIDATIVE STRESS; IN-VITRO; LIPID-METABOLISM;

D O I：

10.1007/s00109-021-02170-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome and, as such, is associated with obesity. With the current and growing epidemic of obesity, NAFLD is already considered the most common liver disease in the world. Currently, there is no official treatment for the disease besides weight loss. Although there are a few synthetic drugs currently being studied, there is also an abundance of herbal products that could also be used for treatment. With the World Health Organization (WHO) traditional medicine strategy (2014-2023) in mind, this review aims to analyze the mechanisms of action of some of these herbal products, as well as evaluate toxicity and herb-drug interactions available in literature.

引用

页码：411 / 425

页数：15

共 160 条

[1] Obesity and its health impact in Africa: a systematic review [J].

Adeboye, Bridget ;

Bermano, Giovanna ;

Rolland, Catherine .

CARDIOVASCULAR JOURNAL OF AFRICA, 2012, 23 (09) :512-521

[2] Effects of resveratrol and other polyphenols in hepatic steatosis [J].

Aguirre, Leixuri ;

Puy Portillo, Maria ;

Hijona, Elizabeth ;

Bujanda, Luis .

WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (23) :7366-7380

[3]

Al-Maamari Jamal Nasser Saleh, 2021, Journal of Basic and Clinical Physiology and Pharmacology, V32, P637, DOI 10.1515/jbcpp-2020-0423

[4]

Apea-Bah FB, 2009, J MED PLANTS RES, V3, P736

[5] Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD [J].

Araujo, Layanne C. C. ;

Feitosa, Karla B. ;

Murata, Gilson M. ;

Furigo, Isadora C. ;

Teixeira, Simone A. ;

Lucena, Camila F. ;

Ribeiro, Luciene M. ;

Muscara, Marcelo N. ;

Costa, Soraia K. P. ;

Donato Jr, Jose ;

Bordin, Silvana ;

Curi, Rui ;

Carvalho, Carla R. O. .

SCIENTIFIC REPORTS, 2018, 8

[6] Effect of resveratrol on metabolic syndrome components: A systematic review and meta-analysis [J].

Asgary, Sedigheh ;

Karimi, Raheleh ;

Momtaz, Saeideh ;

Naseri, Rozita ;

Farzaei, Mohammad Hosein .

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2019, 20 (02) :173-186

[7] In silico and in vitro inhibition of cytochrome P450 3A by synthetic stilbenoids [J].

Basheer, Loai ;

Schultz, Keren ;

Guttman, Yelena ;

Kerem, Zohar .

FOOD CHEMISTRY, 2017, 237 :895-903

[8] Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs:: What is the evidence? [J].

Bone, Kerry Martin .

MOLECULAR NUTRITION & FOOD RESEARCH, 2008, 52 (07) :764-771

[9] Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity [J].

Browning, JD ;

Szczepaniak, LS ;

Dobbins, R ;

Nuremberg, P ;

Horton, JD ;

Cohen, JC ;

Grundy, SM ;

Hobbs, HH .

HEPATOLOGY, 2004, 40 (06) :1387-1395

[10] An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures [J].

Budzinski, JW ;

Foster, BC ;

Vandenhoek, S ;

Arnason, JT .

PHYTOMEDICINE, 2000, 7 (04) :273-282

← 1 2 3 4 5 6 7 8 9 10 →