Cannabinoids:: Potential anticancer agents

被引：523
作者：
Guzmán, M [1 ]
机构：
[1] Univ Complutense, Sch Biol, Dept Biochem & Mol Biol 1, E-28040 Madrid, Spain
来源：
NATURE REVIEWS CANCER | 2003年 / 3卷 / 10期
关键词：
D O I：
10.1038/nrc1188
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cannabinoids - the active components of Cannabis sativa and their derivatives - exert palliative effects in cancer patients by preventing nausea, vomiting and pain and by stimulating appetite. In addition, these compounds have been shown to inhibit the growth of tumour cells in culture and animal models by modulating key cell-signalling pathways. Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies. So, could cannabinoids be used to develop new anticancer therapies?
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页码：745 / 755
页数：11
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