In relation to ethics, current theories and guidelines are often mentioned, which, in fact, shows the lack of an epistemologicall found edethical apparatus, in the absence of which, moral judgment losesits prime reason, name lyvaluing the ethical man - as a person. The meaning of ethical values has been extended and gained various linguistic forms and understandings, basically because the value dimension is not founded on an ethical methodology. How ever, this method requires ethical conceptual clarification on which to build the architecture of knowledge. This idea is in relation with the concept of "epistemological ethics", that we propose to the scientific community for validation. The entire content of this concept is a theoretical link between epistemic and ethical justification, in terms of mind-body ratio, brought in to a unified approach of humanity and knowledge. In the light of this new debate, Roberto Poli's perspective on the need to return to "ontological neglect", "methodological primitivism" and "ignorance of our own roots" Continue sour present research and interrogations and reveals new coordinates of knowledge and understanding.