Idiopathic thrombocytopenic purpura as a hematologic manifestation of COVID-19 infection: A case report

被引:3
作者
Laali, Azadeh [1 ]
Kermanshah, Zohreh [2 ]
Keyvani, Hossein [3 ,4 ]
Kaveh, Vahid [5 ]
Karampoor, Sajad [3 ,4 ]
机构
[1] Iran Univ Med Sci, Firoozgar Hosp, Dept Infect Dis, Tehran, Iran
[2] Iran Univ Med Sci, Sch Med, Tehran, Iran
[3] Iran Univ Med Sci, Gastrointestinal & Liver Dis Res Ctr, Tehran, Iran
[4] Iran Univ Med Sci, Sch Med, Dept Virol, Tehran, Iran
[5] Iran Univ Med Sci, Dept Hematol & Oncol, Tehran, Iran
关键词
Idiopathic thrombocytopenic purpura; COVID-19; Coronavirus; Thrombocytopenia; IMMUNE THROMBOCYTOPENIA; CHILDREN; ADULTS;
D O I
10.1016/j.rmcr.2021.101534
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The hematologic system is one of the vulnerable parts of the human body in coronavirus disease-2019 (COVID-19) infection. Lymphopenia and disseminated intravascular coagulation (DIC) are among the most frequent consequences of COVID-19. Idiopathic thrombocytopenic purpura is one of the common causes of thrombocytopenia in adults. It is defined by thrombocytopenia when platelet counts <10(5)/mu l in the absence of anemia and leukopenia. Traditionally, infections, typically viral, have been known as the main culprits of low platelet counts before the involvement of ITP. According to the literature, C virus (HCV), HIV, varicella-zoster virus (VZV), and cytomegalovirus (CMV) are considered secondary causative agents for the development of ITP. In this study, we reported a case that was afflicted with concurrent severe thrombocytopenia diagnosed as ITP and COVID-19 infection.
引用
收藏
页数:3
相关论文
共 26 条
[1]   Thrombocytopenia as an initial manifestation of COVID-19; case series and literature review [J].
Ahmed, Maria Zahid ;
Khakwani, Muhammad ;
Venkatadasari, Indrani ;
Horgan, Claire ;
Giles, Hannah ;
Jobanputra, Shailesh ;
Lokare, Anand ;
Ewing, Joanne ;
Paneesha, Shankara ;
Murthy, Vidhya .
BRITISH JOURNAL OF HAEMATOLOGY, 2020, 189 (06) :1057-1058
[2]   COVID-19-associated immune thrombocytopenia [J].
Bomhof, Gienke ;
Mutsaers, Pim G. N. J. ;
Leebeek, Frank W. G. ;
te Boekhorst, Peter A. W. ;
Hofland, Johannes ;
Croles, F. Nanne ;
Jansen, A. J. Gerard .
BRITISH JOURNAL OF HAEMATOLOGY, 2020, 190 (02) :E61-E64
[3]   Risk of Immune Thrombocytopenic Purpura and Autoimmune Hemolytic Anemia Among 120 908 US Veterans With Hepatitis C Virus Infection [J].
Chiao, Elizabeth Y. ;
Engels, Eric A. ;
Kramer, Jennifer R. ;
Pietz, Kenneth ;
Henderson, Louise ;
Giordano, Thomas P. ;
Landgren, Ola .
ARCHIVES OF INTERNAL MEDICINE, 2009, 169 (04) :357-363
[4]   How I treat idiopathic thrombocytopenic purpura (ITP) [J].
Cines, DB ;
Bussel, JB .
BLOOD, 2005, 106 (07) :2244-2251
[5]   The ITP syndrome: pathogenic and clinical diversity [J].
Cines, Douglas B. ;
Bussel, James B. ;
Liebman, Howard A. ;
Prak, Eline T. Luning .
BLOOD, 2009, 113 (26) :6511-6521
[6]   Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update [J].
Coopamah, MD ;
Garvey, MB ;
Freedman, J ;
Semple, JW .
TRANSFUSION MEDICINE REVIEWS, 2003, 17 (01) :69-80
[7]   Cytomegalovirus can make immune thrombocytopenic purpura refractory [J].
DiMaggio, Dina ;
Anderson, Alan ;
Bussel, James B. .
BRITISH JOURNAL OF HAEMATOLOGY, 2009, 146 (01) :104-112
[8]   Correction of th1-dominant cytokine profiles by high-dose dexamethasone in patients with chronic idiopathic thrombocytopenic purpura [J].
Guo, Chengshan ;
Chu, Xiaoxia ;
Shi, Yan ;
He, Weidong ;
Li, Lizhen ;
Wang, Lin ;
Wang, Yingxue ;
Peng, Jun ;
Hou, Ming .
JOURNAL OF CLINICAL IMMUNOLOGY, 2007, 27 (06) :557-562
[9]   Extrapulmonary manifestations of COVID-19 [J].
Gupta, Aakriti ;
Madhavan, Mahesh V. ;
Sehgal, Kartik ;
Nair, Nandini ;
Mahajan, Shiwani ;
Sehrawat, Tejasav S. ;
Bikdeli, Behnood ;
Ahluwalia, Neha ;
Ausiello, John C. ;
Wan, Elaine Y. ;
Freedberg, Daniel E. ;
Kirtane, Ajay J. ;
Parikh, Sahil A. ;
Maurer, Mathew S. ;
Nordvig, Anna S. ;
Accili, Domenico ;
Bathon, Joan M. ;
Mohan, Sumit ;
Bauer, Kenneth A. ;
Leon, Martin B. ;
Krumholz, Harlan M. ;
Uriel, Nir ;
Mehra, Mandeep R. ;
Elkind, Mitchell S. V. ;
Stone, Gregg W. ;
Schwartz, Allan ;
Ho, David D. ;
Bilezikian, John P. ;
Landry, Donald W. .
NATURE MEDICINE, 2020, 26 (07) :1017-1032
[10]   The role of lovastatin in the attenuation of COVID-19 [J].
Karampoor, Sajad ;
Hesamizadeh, Khashayar ;
Shams, Zinat ;
Novin, Arefeh Ghafari ;
Farahmand, Mohammad ;
Zahednasab, Hamid ;
Mirzaei, Rasoul ;
Zamani, Farhad ;
Hajibaba, Marzieh ;
Bouzari, Behnaz ;
Laali, Azadeh ;
Tabibzadeh, Alireza ;
Niya, Mohammad Hadi Karbalaie ;
Keyvani, Hossein .
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 101