Nanobubbles for therapeutic delivery: Production, stability and current prospects

被引：46
作者：
Batchelor, Damien V. B. [1 ]
Armistead, Fern J. [1 ]
Ingram, Nicola [2 ]
Peyman, Sally A. [1 ]
Mclaughlan, James R. [2 ,3 ]
Coletta, P. Louise [2 ]
Evans, Stephen D. [1 ]
机构：
[1] Univ Leeds, Mol & Nanoscale Phys Grp, Sch Phys & Astron, Leeds LS2 9JT, W Yorkshire, England
[2] St James Univ Hosp, Wellcome Trust Brenner Bldg, Leeds Inst Med Res, Leeds LS9 7TF, W Yorkshire, England
[3] Univ Leeds, Fac Elect & Elect Engn, Leeds LS2 9JT, W Yorkshire, England
来源：
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2021年 / 54卷 / 54期
基金：
英国工程与自然科学研究理事会; 英国医学研究理事会;
关键词：
Nanobubbles;   Ultrafine bubbles; Ultrasound; Triggered release; Drug delivery  Therapeutic  Theranostic  Chemotherapy  Cancer  Biomedical; CONTRAST-ENHANCED ULTRASOUND; DRUG-DELIVERY; MACROMOLECULAR THERAPEUTICS; MICROBUBBLE POPULATIONS; SILICA NANOPARTICLES; ECHOGENIC LIPOSOMES; POLYMERIC MICELLES; PLGA NANOBUBBLES; TARGETED THERAPY; CANCER-CELLS;
D O I：
10.1016/j.cocis.2021.101456
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Nanobubbles (NBs) have recently garnered widespread attention for their potential use as dual diagnostic and therapeutic agents. Similar to their micron-sized relatives (microbubbles), NBs are shell-stabilized, gas-cored bubbles that in conjunction with ultrasound can be used to increase imaging contrast, as well as provide a mechanism for trigger drug release and increased therapeutic delivery. In this review, we specifically focus on their development as agents to enhance drug delivery, discussing theory, characterization techniques, key formulations and prospects for translation into clinical use.
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页数：24
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共 160 条
  • [61] Engineering oxygen nanobubbles for the effective reversal of hypoxia
    Khan, Muhammad Saad
    Hwang, Jangsun
    Seo, Youngmin
    Shin, Kyusoon
    Lee, Kyungwoo
    Park, Chanhwi
    Choi, Yonghyun
    Hong, Jong Wook
    Choi, Jonghoon
    [J]. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2018, 46 : S318 - S327
  • [62] Surface Composition and Preparation Method for Oxygen Nanobubbles for Drug Delivery and Ultrasound Imaging Applications
    Khan, Muhammad Saad
    Hwang, Jangsun
    Lee, Kyungwoo
    Choi, Yonghyun
    Jang, Jaehee
    Kwon, Yejin
    Hong, Jong Wook
    Choi, Jonghoon
    [J]. NANOMATERIALS, 2019, 9 (01)
  • [63] Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression
    Klegerman, Melvin E.
    Naji, Ali K.
    Haworth, Kevin J.
    Zou, Yuejiao
    Golunski, Eva
    Peng, Tao
    Britton, George L.
    Huang, Shao-Ling
    Holland, Christy K.
    McPherson, David D.
    [J]. JOURNAL OF LIPOSOME RESEARCH, 2016, 26 (01) : 47 - 56
  • [64] Ultrasound-triggered release of materials entrapped in microbubble-liposome constructs: A tool for targeted drug delivery
    Klibanov, Alexander L.
    Shevchenko, Talent I.
    Raju, Balasundar I.
    Seip, Ralf
    Chin, Chien T.
    [J]. JOURNAL OF CONTROLLED RELEASE, 2010, 148 (01) : 13 - 17
  • [65] Increasing the Endothelial Layer Permeability Through Ultrasound-Activated Microbubbles
    Kooiman, Klazina
    Emmer, Marcia
    Foppen-Harteveld, Miranda
    van Wamel, Annemieke
    de Jong, Nico
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2010, 57 (01) : 29 - 32
  • [66] Oil-filled polymer microcapsules for ultrasound-mediated delivery of lipophilic drugs
    Kooiman, Klazina
    Bohmer, Marcel R.
    Emmer, Marcia
    Vos, Hendrik J.
    Chlon, Ceciel
    Shi, William T.
    Hall, Christopher S.
    de Winter, Suzanne H. P. M.
    Schroen, Karin
    Versluis, Michel
    de Jong, Nico
    van Wamel, Annemieke
    [J]. JOURNAL OF CONTROLLED RELEASE, 2009, 133 (02) : 109 - 118
  • [67] Formulation and Characterization of Echogenic Lipid-Pluronic Nanobubbles
    Krupka, Tianyi M.
    Solorio, Luis
    Wilson, Robin E.
    Wu, Hanping
    Azar, Nami
    Exner, Agata A.
    [J]. MOLECULAR PHARMACEUTICS, 2010, 7 (01) : 49 - 59
  • [68] Lipid monolayer collapse and microbubble stability
    Kwan, James J.
    Borden, Mark A.
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2012, 183 : 82 - 99
  • [69] Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model
    Laing, Susan T.
    Moody, Melanie R.
    Kim, Hyunggun
    Smulevitz, Beverly
    Huang, Shao-Ling
    Holland, Christy K.
    McPherson, David D.
    Klegerman, Melvin E.
    [J]. THROMBOSIS RESEARCH, 2012, 130 (04) : 629 - 635
  • [70] Physics of bubble oscillations
    Lauterborn, Werner
    Kurz, Thomas
    [J]. REPORTS ON PROGRESS IN PHYSICS, 2010, 73 (10)
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