Indications and complications of transfusions in sickle cell disease

被引：38

作者：

Smith-Whitley, Kim ^{[1
]}

Thompson, Alexis A. ^{[2
]}

机构：

[1] Childrens Hosp Philadelphia, Div Hematol, Sickle Cell Clin Program, Philadelphia, PA 19104 USA

[2] Childrens Mem Hosp, Chicago, IL 60614 USA

来源：

PEDIATRIC BLOOD & CANCER | 2012年 / 59卷 / 02期

关键词：

alloimmunization; red cell transfusion indications; sickle cell disease; transfusional iron overload; ACUTE CHEST SYNDROME; RED-BLOOD-CELLS; IRON-OVERLOADED PATIENTS; STROKE-PREVENTION TRIAL; CLINICAL-SIGNIFICANCE; HYDROXYUREA SWITCH; PEDIATRIC-PATIENTS; BETA-THALASSEMIA; CHILDREN; ANEMIA;

D O I：

10.1002/pbc.24179

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Red cell transfusion remains an important part of the management of acute and chronic complications in SCD. The ongoing and emerging uses of transfusions in SCD may have significant benefits; however, the potential complications of transfusions also deserve careful consideration. In this report we review current indications for transfusions, transfusion complications, modifications of transfusion practices to mitigate risk, and potential considerations to improve transfusion outcomes. Pediatr Blood Cancer 2012;59:358364. (c) 2012 Wiley Periodicals, Inc.

引用

页码：358 / 364

页数：7

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