Centromere proteins and chromosome inheritance: a complex affair

被引：69
作者：
Dobie, KW [1 ]
Hari, KL [1 ]
Maggert, KA [1 ]
Karpen, GH [1 ]
机构：
[1] Salk Inst Biol Studies, Mol Biol & Virol Lab, La Jolla, CA 92037 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1999年 / 9卷 / 02期
关键词：
D O I：
10.1016/S0959-437X(99)80031-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Centromeres and the associated kinetochores are involved in essential aspects of chromosome transmission, Recent advances have included the identification and understanding of proteins that have a pivotal role in centromere structure, kinetochore formation, and the coordination of chromosome inheritance with the cell cycle in several organisms. A picture is beginning to emerge of the centromere-kinetechore as a complex and dynamic structure with conservation of function at the protein level across diverse species.
引用
收藏
页码：206 / 217
页数：12
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