Antiplatelet therapy after percutaneous coronary intervention: current status and future perspectives

被引：34

作者：

Natsuaki, Masahiro ^{[1
]}

Sonoda, Shinjo ^{[1
]}

Yoshioka, Goro ^{[1
]}

Hongo, Hiroshi ^{[1
]}

Kaneko, Tetsuya ^{[1
]}

Kashiyama, Kuninobu ^{[1
]}

Yokoi, Kensuke ^{[1
]}

Hikichi, Yutaka ^{[2
]}

Node, Koichi ^{[1
]}

机构：

[1] Saga Univ Hosp, Dept Cardiovasc Med, 5-1-1 Nabeshima, Saga 8498501, Japan

[2] Saga Med Ctr, Cardiovasc Ctr, Koseikan, Saga, Japan

来源：

CARDIOVASCULAR INTERVENTION AND THERAPEUTICS | 2022年 / 37卷 / 02期

关键词：

Antiplatelet therapy; Antithrombotic therapy; Percutaneous coronary intervention; ELUTING STENT IMPLANTATION; ARTERY-DISEASE; CARDIOVASCULAR EVENTS; ATRIAL-FIBRILLATION; OPTIMAL DURATION; VASCULAR EVENTS; FOCUSED UPDATE; DOUBLE-BLIND; CLOPIDOGREL; ASPIRIN;

D O I：

10.1007/s12928-022-00847-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antiplatelet therapy after percutaneous coronary intervention (PCI) has been changing in parallel with the development of drug-eluting stents (DES) and antiplatelet agents. The recommendation of dual antiplatelet therapy duration is getting shorter due to the decreased risk of stent thrombosis in new-generation DES, the use of a P2Y(12) inhibitor as a monotherapy, and the increasing prevalence of high bleeding risk patients. Antithrombotic therapy after PCI has also changed due to the introduction of direct oral anticoagulants. Aspirin-free P2Y(12) inhibitor monotherapy is now being evaluated in several prospective studies as a novel strategy of antiplatelet therapy after PCI. This review shows a current status and provides future perspectives for the antiplatelet therapy after PCI.

引用

页码：255 / 263

页数：9

共 68 条

[1] Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation [J].

Cannon, Christopher P. ;

Bhatt, Deepak L. ;

Oldgren, Jonas ;

Lip, Gregory Y. H. ;

Ellis, Stephen G. ;

Kimura, Takeshi ;

Maeng, Michael ;

Merkely, Bela ;

Zeymer, Uwe ;

Gropper, Savion ;

Nordaby, Matias ;

Kleine, Eva ;

Harper, Ruth ;

Manassie, Jenny ;

Januzzi, James L. ;

ten Berg, Jurrien M. ;

Steg, Gabriel ;

Hohnloser, Stefan H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (16) :1513-1524

[2] Monotherapy with a P2Y 12 inhibitor or aspirin for secondary prevention in patients with established atherosclerosis: a systematic review and meta-analysis [J].

Chiarito, Mauro ;

Sanz-Sanchez, Jorge ;

Cannata, Francesco ;

Cao, Davide ;

Sturla, Matteo ;

Panico, Cristina ;

Godino, Cosmo ;

Regazzoli, Damiano ;

Reimers, Bernhard ;

De Caterina, Raffaele ;

Condorelli, Gianluigi ;

Ferrante, Giuseppe ;

Stefanini, Giulio G. .

LANCET, 2020, 395 (10235) :1487-1495

[3]

Collet JP, 2021, REV ESP CARDIOL, V74, DOI [10.1016/j.rec.2021.05.002, 10.1093/eurheartj/ehaa575]

[4] Dual-antiplatelet treatment beyond 1 year after drug-eluting stent implantation (ARCTIC-Interruption): a randomised trial [J].

Collet, Jean-Philippe ;

Silvain, Johanne ;

Barthelemy, Olivier ;

Range, Gregoire ;

Cayla, Guillaume ;

Van Belle, Eric ;

Cuisset, Thomas ;

Elhadad, Simon ;

Schiele, Francois ;

Lhoest, Nicolas ;

Ohlmann, Patrick ;

Carrie, Didier ;

Rousseau, Helene ;

Aubry, Pierre ;

Monsegu, Jacques ;

Sabouret, Pierre ;

O'Connor, Stephen A. ;

Abtan, Jeremie ;

Kerneis, Mathieu ;

Saint-Etienne, Christophe ;

Beygui, Farzin ;

Vicaut, Eric ;

Montalescot, Gilles .

LANCET, 2014, 384 (9954) :1577-1585

[5] Second-Generation Drug-Eluting Stent Implantation Followed by 6-Versus 12-Month Dual Antiplatelet Therapy The SECURITY Randomized Clinical Trial [J].

Colombo, Antonio ;

Chieffo, Alaide ;

Frasheri, Arian ;

Garbo, Roberto ;

Masotti-Centol, Monica ;

Salvatella, Neus ;

Dominguez, Juan Francisco Oteo ;

Steffanon, Luigi ;

Tarantini, Giuseppe ;

Presbitero, Patrizia ;

Menozzi, Alberto ;

Pucci, Edoardo ;

Mauri, Josepa ;

Cesana, Bruno Mario ;

Giustino, Gennaro ;

Sardella, Gennaro .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 64 (20) :2086-2097

[6] Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial [J].

Connolly, S. ;

Pogue, J. ;

Hart, R. ;

Pfeffer, M. ;

Hohnloser, S. ;

Chrolavicius, S. ;

Yusuf, S. .

LANCET, 2006, 367 (9526) :1903-1912

[7] Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial [J].

Dewilde, Willem J. M. ;

Oirbans, Tom ;

Verheugt, Freek W. A. ;

Kelder, Johannes C. ;

De Smet, Bart J. G. L. ;

Herrman, Jean-Paul ;

Adriaenssens, Tom ;

Vrolix, Mathias ;

Heestermans, Antonius A. C. M. ;

Vis, Marije M. ;

Tijsen, Jan G. P. ;

van 't Hof, Arnoud W. ;

ten Berg, Jurrien M. .

LANCET, 2013, 381 (9872) :1107-1115

[8] Three vs Twelve Months of Dual Antiplatelet Therapy After Zotarolimus-Eluting Stents The OPTIMIZE Randomized Trial [J].

Feres, Fausto ;

Costa, Ricardo A. ;

Abizaid, Alexandre ;

Leon, Martin B. ;

Marin-Neto, J. Antonio ;

Botelho, Roberto V. ;

King, Spencer B., III ;

Negoita, Manuela ;

Liu, Minglei ;

de Paula, J. Eduardo T. ;

Mangione, Jose A. ;

Meireles, George X. ;

Castello, Helio J., Jr. ;

Nicolela, Eduardo L., Jr. ;

Perin, Marco A. ;

Devito, Fernando S. ;

Labrunie, Andre ;

Salvadori, Decio, Jr. ;

Gusmao, Marcos ;

Staico, Rodolfo ;

Costa, J. Ribamar ;

de Castro, Juliana P. ;

Abizaid, Andrea S. ;

Bhatt, Deepak L. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (23) :2510-2522

[9] Prevention of Bleeding in Patients with Atrial Fibrillation Undergoing PCI [J].

Gibson, C. Michael ;

Mehran, Roxana ;

Bode, Christoph ;

Halperin, Jonathan ;

Verheugt, Freek W. ;

Wildgoose, Peter ;

Birmingham, Mary ;

Ianus, Juliana ;

Burton, Paul ;

van Eickels, Martin ;

Korjian, Serge ;

Daaboul, Yazan ;

Lip, Gregory Y. H. ;

Cohen, Marc ;

Husted, Steen ;

Peterson, Eric D. ;

Fox, Keith A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (25) :2423-2434

[10] 6-Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin The Randomized, Multicenter ITALIC Trial [J].

Gilard, Martine ;

Barragan, Paul ;

Noryani, Arif A. L. ;

Noor, Hussam A. ;

Majwal, Talib ;

Hovasse, Thomas ;

Castellant, Philippe ;

Schneeberger, Michel ;

Maillard, Luc ;

Bressolette, Erwan ;

Wojcik, Jaroslaw ;

Delarche, Nicolas ;

Blanchard, Didier ;

Jouve, Bernard ;

Ormezzano, Olivier ;

Paganelli, Franck ;

Levy, Gilles ;

Sainsous, Joel ;

Carrie, Didier ;

Furber, Alain ;

Berland, Jacques ;

Darremont, Oliver ;

Le Breton, Herve ;

Lyuycx-Bore, Anne ;

Gommeaux, Antoine ;

Cassat, Claude ;

Kermarrec, Alain ;

Cazaux, Pierre ;

Druelles, Philippe ;

Dauphin, Raphael ;

Armengaud, Jean ;

Dupouy, Patrick ;

Champagnac, Didier ;

Ohlmann, Patrick ;

Endresen, Knut ;

Benamer, Hakim ;

Kiss, Robert Gabor ;

Ungi, Imre ;

Boschat, Jacques ;

Morice, Marie-Claude .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (08) :777-786

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