Antiplatelet therapy after percutaneous coronary intervention (PCI) has been changing in parallel with the development of drug-eluting stents (DES) and antiplatelet agents. The recommendation of dual antiplatelet therapy duration is getting shorter due to the decreased risk of stent thrombosis in new-generation DES, the use of a P2Y(12) inhibitor as a monotherapy, and the increasing prevalence of high bleeding risk patients. Antithrombotic therapy after PCI has also changed due to the introduction of direct oral anticoagulants. Aspirin-free P2Y(12) inhibitor monotherapy is now being evaluated in several prospective studies as a novel strategy of antiplatelet therapy after PCI. This review shows a current status and provides future perspectives for the antiplatelet therapy after PCI.
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Toronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
Freeman Rd Hosp, Cardiothorac Ctr, Newcastle Upon Tyne, Tyne & Wear, England
Newcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, Tyne & Wear, EnglandToronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
Alkhalil, Mohammad
Dzavik, Vladimir
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Toronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, CanadaToronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
Dzavik, Vladimir
Bhatt, Deepak L.
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Harvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, Boston, MA 02115 USAToronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
Bhatt, Deepak L.
Mehran, Roxana
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Icahn Sch Med Mt Sinai, New York, NY 10029 USAToronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
Mehran, Roxana
Mehta, Shamir R.
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McMaster Univ, Populat Hlth Res Inst, Hamilton, ON, Canada
Hamilton Hlth Sci, Hamilton, ON, CanadaToronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiol, Toronto, ON, Canada
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Univ Sheffield, Sch Med & Populat Hlth, Div Clin Med, Cardiovasc Res Unit, Sheffield, England
Sheffield Teaching Hosp NHS Fdn Trust, NIHR Sheffield Biomed Res Ctr, Sheffield, EnglandUniv Sheffield, Sch Med & Populat Hlth, Div Clin Med, Cardiovasc Res Unit, Sheffield, England
Sammut, Mark Anthony
Storey, Robert F.
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Univ Sheffield, Sch Med & Populat Hlth, Div Clin Med, Cardiovasc Res Unit, Sheffield, England
Sheffield Teaching Hosp NHS Fdn Trust, NIHR Sheffield Biomed Res Ctr, Sheffield, EnglandUniv Sheffield, Sch Med & Populat Hlth, Div Clin Med, Cardiovasc Res Unit, Sheffield, England
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Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Albert Einstein Coll Med, Jacobi Med Ctr, Dept Internal Med, Bronx, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Chandiramani, Rishi
Spirito, Alessandro
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Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Spirito, Alessandro
Johnson, James W.
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Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Johnson, James W.
Mehta, Adhya
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Albert Einstein Coll Med, Jacobi Med Ctr, Dept Internal Med, Bronx, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Mehta, Adhya
Vogel, Birgit
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Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Vogel, Birgit
Faillace, Robert T.
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Albert Einstein Coll Med, Jacobi Med Ctr, Dept Internal Med, Bronx, NY USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Faillace, Robert T.
Mehran, Roxana
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Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA
Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, Ctr Intervent Cardiovasc Res & Clin Trials, One Gustave L Levy Pl, New York, NY 10029 USAIcahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, New York, NY USA