Biofunctionalization of nanoparticles for cytosensing and cell surface carbohydrate assay

被引：18

作者：

Ding, Lin ^{[1
]}

Ju, Huangxian ^{[1
]}

机构：

[1] Nanjing Univ, Dept Chem, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2011年 / 21卷 / 45期

基金：

中国国家自然科学基金;

关键词：

IRON-OXIDE NANOPARTICLES; SEMICONDUCTING POLYMER DOTS; MULTIFUNCTIONAL MAGNETIC NANOPARTICLES; APTAMER-CONJUGATED NANOPARTICLES; BIOCOMPATIBLE QUANTUM DOTS; ENHANCED RAMAN-SCATTERING; RESONANCE ENERGY-TRANSFER; DRUG-SENSITIVITY TEST; LEUKEMIA K562 CELLS; IN-VIVO;

D O I：

10.1039/c1jm13700j

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Developing sensitive and specific sensing strategies for probing the chemical and biological events in/at a living cell can ultimately contribute to the understanding of life processes. These strategies are also beneficial to early diagnosis of diseases for early and successful treatment. Biofunctionalization of nanoparticles can integrate remarkable properties of both biological components and nanoparticles, thus providing a promising platform for tracing the recognition and transduction processes and improving the sensing performance. This Feature Article reviews the current research regarding the biofunctionalization strategies, and the usage of the bionanocomposites in the arena of cytosensing and cell surface carbohydrate assay.

引用

页码：18154 / 18173

页数：20

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