Formal synthesis of schulzeines B and C

被引：19

作者：

Kuntiyong, Punlop ^{[1
]}

Akkarasamiyo, Sunisa ^{[1
]}

Piboonsrinakara, Nuanpan ^{[1
]}

Hemmara, Chitlada ^{[1
]}

Songthammawat, Poramate ^{[1
]}

机构：

[1] Silpakorn Univ, Fac Sci, Dept Chem, Nakhon Pathom 73000, Thailand

来源：

TETRAHEDRON | 2011年 / 67卷 / 41期

关键词：

Schulzeines B and C; Formal synthesis; N-Acyliminium ion cyclization; 28-Carbon fatty acid side chain; ALPHA-GLUCOSIDASE INHIBITORS;

D O I：

10.1016/j.tet.2011.07.085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal synthesis of schulzeines B and C, marine natural products with inhibitory effect against alpha-glucosidase, has been achieved. The key reactions of the synthesis are N-acyliminium ion cyclization, Sharpless asymmetric dihydroxylation, olefin cross metathesis, and asymmetric allylboration. (C) 2011 Elsevier Ltd. All rights reserved.

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收藏

页码：8034 / 8040

页数：7

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