Effect on diagnostic yield of repeated stool testing during outbreaks of Clostridium difficile-associated disease

被引：21

作者：

Debast, S. B. ^{[1
]}

van Kregten, E. ^{[1
]}

Oskam, K. M. G. ^{[1
]}

van den Berg, T.

Van den Berg, R. J. ^{[2
]}

Kuijper, E. J. ^{[2
]}

机构：

[1] Meander Med Ctr, Dept Med Microbiol, NL-3800 BM Amersfoort, Netherlands

[2] Leiden Univ, Med Ctr, Ctr Infect Dis, Reference Lab Clostrisium Difficile,Dept Med Micr, Leiden, Netherlands

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷 / 06期

关键词：

Clostridium difficile; diagnostic yield; diarrhoea; immunoassay; repeated tests; toxin detection;

D O I：

10.1111/j.1469-0691.2008.01999.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The effect on diagnostic yield of testing sequential stools was assessed during two hospital epidemics of Clostridium difficile. Using a rapid immunoassay, C. difficile-associated disease was diagnosed in 237 diarrhoeal patients, of whom 204 (86%) were diagnosed from the first faeces sample and 12 (5%) were diagnosed from follow-up samples obtained within 1 week. The remaining 21 (9%) patients yielded a positive test from stools obtained > 1 week after the initial negative sample. It was concluded that repeated testing of stools for C. difficile toxin is of value in controlling outbreaks of C. difficile infection.

引用

页码：622 / 624

页数：3

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