HIV infection and bone disease: implications for an aging population

被引：12

作者：

Cotter, Aoife G. ^{[1
,2
]}

Mallon, Patrick W. G. ^{[1
,2
]}

机构：

[1] Univ Coll Dublin 7, Sch Med & Med Sci, HIV Mol Res Grp, Dublin, Ireland

[2] Mater Misericordiae Univ Hosp, Dept Infect Dis, Dublin 7, Ireland

来源：

SEXUAL HEALTH | 2011年 / 8卷 / 04期

关键词：

antiretroviral therapy; bone mineral density; osteopaenia; osteoporosis; VITAMIN-D DEFICIENCY; TENOFOVIR DISOPROXIL FUMARATE; ACTIVE ANTIRETROVIRAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; MINERAL DENSITY; FRACTURE RISK; POSTMENOPAUSAL OSTEOPOROSIS; OLDER MEN; NONVERTEBRAL FRACTURES; GENERAL-POPULATION;

D O I：

10.1071/SH11014

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Now more than ever, the management of age-related problems, from cardiovascular morbidity to bone pathology, is increasingly relevant for HIV physicians. Low bone mineral density (BMD) and fractures are more common in HIV-infected patients. Although a multifactorial aetiology underlies this condition, increasing evidence suggests a role for antiretroviral therapy in low BMD, especially upon initiation. This review will detail the epidemiology, pathogenesis, diagnosis and management of osteoporosis and low BMD in HIV-infected patients, with particular emphasis on aging.

引用

页码：493 / 501

页数：9

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