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- [32] The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutationsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (09) : 2959 - 2966Tucker, Thomas J.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USASaggar, Sandeep论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USASisko, John T.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USATynebor, Robert M.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAWilliams, Theresa M.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAFelock, Peter J.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Antiviral Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAFlynn, Jessica A.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Vaccines & Biol Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USALai, Ming-Tain论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Antiviral Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USALiang, Yuexia论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Drug Metab, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAMcGaughey, Georgia论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USALiu, Meiquing论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Antiviral Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAMiller, Mike论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Antiviral Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAMoyer, Gregory论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Vaccines & Biol Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAMunshi, Vandna论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Antiviral Res, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAPerlow-Poehnelt, Rebecca论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAPrasad, Sridhar论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USASanchez, Rosa论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Drug Metab, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USATorrent, Maricel论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAVacca, Joseph P.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAWan, Bang-Lin论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USAYan, Youwei论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA Merck Res Labs, Dept Med Chem & Struct Biol, West Point, PA 19486 USA
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- [34] Escaping from Flatland: Multiparameter Optimization Leads to the Discovery of Novel Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Human Immunodeficiency Virus-1 Non-nucleoside Reverse Transcriptase Inhibitors with Superior Antiviral Activities against Non-nucleoside Reverse Transcriptase Inhibitor-Resistant Variants and Favorable Drug-like ProfilesJOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (13) : 8643 - 8665Wang, Zhao论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaSharma, Prem Prakash论文数: 0 引用数: 0 h-index: 0机构: Univ Delhi, Hansraj Coll, Dept Chem, Lab Translat Chem & Drug Discovery, Delhi 110007, India Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaRathi, Brijesh论文数: 0 引用数: 0 h-index: 0机构: Univ Delhi, Hansraj Coll, Dept Chem, Lab Translat Chem & Drug Discovery, Delhi 110007, India Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaXie, Minghui论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaDe Clercq, Erik论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Rega Inst Med Res, Lab Virol & Chemotherapy, B-3000 Leuven, Belgium Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaPannecouque, Christophe论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Rega Inst Med Res, Lab Virol & Chemotherapy, B-3000 Leuven, Belgium Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaKang, Dongwei论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China China Belgium Collaborat Res Ctr Innovat Antiviral, Jinan 250012, Shandong, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaZhan, Peng论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China China Belgium Collaborat Res Ctr Innovat Antiviral, Jinan 250012, Shandong, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R ChinaLiu, Xinyong论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China China Belgium Collaborat Res Ctr Innovat Antiviral, Jinan 250012, Shandong, Peoples R China Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Dept Med Chem,Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China
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