Metal-free oxidative amidation of aldehydes with aminopyridines employing aqueous hydrogen peroxide

被引：34

作者：

Devi, E. Sankari ^{[1
]}

Alanthadka, Anitha ^{[1
]}

Tamilselvi, A. ^{[2
]}

Nagarajan, Subbiah ^{[1
]}

Sridharan, Vellaisamy ^{[1
]}

Maheswari, C. Uma ^{[1
]}

机构：

[1] SASTRA Univ, Sch Chem & Biotechnol, Dept Chem, Organ Synth Grp, Thanjavur 613401, India

[2] Thiagarajar Coll, Dept Chem, Madurai 625009, Tamil Nadu, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2016年 / 14卷 / 35期

关键词：

AMIDE; CARBENE;

D O I：

10.1039/c6ob01454b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first metal free report on the amidation of aldehydes with aminopyridines was accomplished using simple aqueous hydrogen peroxide (aq. H2O2) as the oxidant. No catalysts or additives were needed for this transformation and the reaction proceeded in water, an environmentally benign reaction medium. Green oxidant and reaction conditions, and the ability to construct diverse N-(pyridin-2-yl)benzamide by this elegant method render it a practical alternative for the synthesis of these amides.

引用

页码：8228 / 8231

页数：4

共 50 条

[1] Metal-free pinnick-type oxidative amidation of aldehydes
Goh, Kien Soon
Tan, Choon-Hong
RSC ADVANCES, 2012, 2 (13): : 5536 - 5538
[2] Pd-catalyzed oxidative amidation of aldehydes with hydrogen peroxide
Suto, Yutaka
Yamagiwa, Noriyuki
Torisawa, Yasuhiro
TETRAHEDRON LETTERS, 2008, 49 (40) : 5732 - 5735
[3] Metal-free synthesis of amides by oxidative amidation of aldehydes with amines in PEG/oxidant system
Liang, Jun
Lv, Jing
Shang, Zhi-cai
TETRAHEDRON, 2011, 67 (44) : 8532 - 8535
[4] Metal-Free Oxidative Amidation of Aromatic Aldehydes using an Anthraquinone-Based Organophotocatalyst
Inagawa, Hisamori
Uchida, Seiichiro
Yamaguchi, Eiji
Itoh, Akichika
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 8 (08) : 1411 - 1414
[5] Direct oxidative amidation of aromatic aldehydes using aqueous hydrogen peroxide in continuous flow microreactor systems
Liu, Xiaoying
Jensen, Klavs F.
GREEN CHEMISTRY, 2012, 14 (05) : 1471 - 1474
[6] Oxidative Amidation of Methylarenes and Heteroamines under Metal-Free Conditions
Pappula, Venkatanarayana
Ravi, Chitrakar
Samanta, Supravat
Adimurthy, Subbarayappa
CHEMISTRYSELECT, 2017, 2 (21): : 5887 - 5890
[7] Copper-catalyzed highly efficient oxidative amidation of aldehydes with 2-aminopyridines in an aqueous micellar system
Patel, Om P. S.
Anand, Devireddy
Maurya, Rahul K.
Yadav, Prem P.
GREEN CHEMISTRY, 2015, 17 (07) : 3728 - 3732
[8] Naphthalene Monoanhydride and Perylene Composites for Efficient Photocatalytic Hydrogen Evolution and Metal-Free Heterogeneous Oxidative Amidation
Kumari, Anita
Roy, Raj Sekhar
Gautam, Ujjal K.
Sengupta, Sanchita
ACS APPLIED MATERIALS & INTERFACES, 2024, 16 (43) : 59234 - 59244
[9] On the paradox of transition metal-free alumina-catalyzed epoxidation with aqueous hydrogen peroxide
Rinaldi, R
Schuchardt, U
JOURNAL OF CATALYSIS, 2005, 236 (02) : 335 - 345
[10] METAL-FREE, ONE-POT OXIDATIVE CONVERSION OF ALDEHYDES TO PRIMARY THIOAMIDES IN AQUEOUS MEDIA
Yadav, Arvind K.
Srivastava, Vishnu P.
Yadav, Lal Dhar S.
SYNTHETIC COMMUNICATIONS, 2014, 44 (03) : 408 - 416

← 1 2 3 4 5 →