Indirect detection of hydroxyl radicals using spin trapping and gas chromatography-mass spectrometry

被引：3

作者：

Mistry, Pritesh ^{[1
]}

Najim, Nigar ^{[1
]}

Purdie, Ashley ^{[1
]}

Podmore, Ian ^{[1
]}

机构：

[1] Univ Salford, Biomed Sci Res Inst, Sch Environm & Life Sci, Salford M5 4WT, Lancs, England

来源：

JOURNAL OF CHEMICAL RESEARCH | 2008年 / 07期

关键词：

spin trapping; gas chromatography-mass spectrometry; alpha-[4-pyridyl N-oxide]-N-t-butyl nitrone; free radicals; Fenton reaction;

D O I：

10.3184/030823408785702391

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, hydroxyl radicals have been converted into methyl radicals by reaction with DMSO which, following capture by the spin-trap alpha-[4-pyridyl N-oxide]-N-t-butyl nitrone (POBN, 1), produced a novel dimethyl product (POBN-Me-2, 3) identified by GC-MS. Identification was confirmed when DMSO was replaced by a deuterated analogue (d(6)-DMSO).

引用

页码：395 / 397

页数：3

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