Indirect detection of hydroxyl radicals using spin trapping and gas chromatography-mass spectrometry

被引：3
|
作者：
Mistry, Pritesh [1 ]
Najim, Nigar [1 ]
Purdie, Ashley [1 ]
Podmore, Ian [1 ]
机构：
[1] Univ Salford, Biomed Sci Res Inst, Sch Environm & Life Sci, Salford M5 4WT, Lancs, England
来源：
JOURNAL OF CHEMICAL RESEARCH | 2008年 / 07期
关键词：
spin trapping; gas chromatography-mass spectrometry; alpha-[4-pyridyl N-oxide]-N-t-butyl nitrone; free radicals; Fenton reaction;
D O I：
10.3184/030823408785702391
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this study, hydroxyl radicals have been converted into methyl radicals by reaction with DMSO which, following capture by the spin-trap alpha-[4-pyridyl N-oxide]-N-t-butyl nitrone (POBN, 1), produced a novel dimethyl product (POBN-Me-2, 3) identified by GC-MS. Identification was confirmed when DMSO was replaced by a deuterated analogue (d(6)-DMSO).
引用
收藏
页码：395 / 397
页数：3
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