[1] Univ Hosp Southampton NHS Fdn Trust, Anaesthesia & Crit Care Res Unit, Southampton, Hants, England
[2] Univ Hosp Southampton NHS Fdn Trust, Natl Inst Hlth Res Resp Biomed Res Unit, Crit Care Res Area, Southampton, Hants, England
[3] Univ Southampton, Integrat Physiol & Crit Illness Grp, Clin & Expt Sci, Fac Med, Southampton, Hants, England
[4] Plymouth Hosp NHS Trust Hosp, Dept Anaesthesia & Crit Care Med, Plymouth, Devon, England
[5] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, England
[6] Freeman Rd Hosp, Dept Perioperat Med, Newcastle Upon Tyne, Tyne & Wear, England
[7] Freeman Rd Hosp, Dept Crit Care Med, Newcastle Upon Tyne, Tyne & Wear, England
[8] Torbay Hosp, Dept Anaesthesia & Crit Care Med, Torquay, England