New paraconic acids from the endophytic fungus Xylariaceae sp. J4

被引：2

作者：

Yuan, Chao ^{[1
]}

Shu, Xue-Chun ^{[2
]}

Fan, Lin ^{[3
]}

Zhang, Ying-Bo ^{[1
]}

Guan, Ling-Liang ^{[1
]}

Yu, Fu-Lai ^{[1
]}

Chen, Xiao-Lu ^{[1
]}

Li, Gang ^{[4
]}

机构：

[1] Chinese Acad Trop Agr Sci, Hainan Prov Engn Res Ctr Trop Med Plants, Trop Crops Genet Resources Inst, Danzhou, Peoples R China

[2] Hainan Univ, Coll Forestry, Haikou, Hainan, Peoples R China

[3] Weihai Vocat Coll, Dept Biol & Chem Engn, Weihai, Peoples R China

[4] Qingdao Univ, Sch Pharm, Dept Nat Med Chem & Pharmacognosy, Qingdao 266021, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 01期

基金：

海南省自然科学基金; 中国国家自然科学基金;

关键词：

Endophytes; Xylariaceae sp; secondary metabolites; paraconic acids; antibacterial activities; METABOLITES;

D O I：

10.1080/14786419.2020.1768088

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Three new paraconic acids, xylariacinics A-C (1-3), were isolated from the endophyte Xylariaceae sp. J4 harbored in the medicinal plant Blumea balsamifera. Their structures were elucidated on the basis of extensive spectroscopic data including HRMS, and NMR. The antibacterial efficacies of compounds 1-3 were evaluated against a panel of bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. Their antifungal activities were also tested against Colletotrichum gloeosporioides. Unfortunately, all of them were inactive.

引用

页码：130 / 135

页数：6

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