Synthesis of the tricyclic core structure of vindoline

被引：24
|
作者：
Guo, ZH [1 ]
Schultz, AG [1 ]
机构：
[1] Rensselaer Polytech Inst, Dept Chem, Troy, NY 12180 USA
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 05期
关键词：
vindoline; synthesis; 1,3-dipolar cycloaddition; birch reduction-alkylation;
D O I：
10.1016/j.tetlet.2003.11.115
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of the core tricyclic structure (18) of vindoline has been achieved using the strategy, which features an intramolecular 1,3-dipolar cycloaddition of the azido dienone (12) to give aziridine (13) with complete region- and stereocontrol. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：919 / 921
页数：3
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