COVID-19: vaccination vs. hospitalization

被引：33

作者：

Uzun, Oguz ^{[1
,41
]}

Akpolat, Tekin ^{[2
]}

Varol, Ayhan ^{[3
]}

Turan, Sema ^{[4
]}

Bektas, Serife Gokbulut ^{[4
]}

Cetinkaya, Pelin Duru ^{[5
]}

Dursun, Mazlum ^{[6
]}

Bakan, Nurten ^{[7
]}

Ketencioglu, Burcu Baran ^{[8
]}

Bayrak, Murat ^{[3
]}

Baris, Serap Argun ^{[9
]}

Guner, Rahmet ^{[10
]}

Gunal, Ozgur ^{[11
]}

Nural, Serkan ^{[12
]}

Deniz, Pelin Pinar ^{[13
]}

Toprak, Oya Baydar ^{[14
]}

Ozkan, Gulcihan ^{[15
,16
]}

Gumus, Ayca ^{[3
]}

Kerget, Ferhan ^{[17
]}

Ercelik, Merve ^{[18
]}

Ataoglu, Ozlem ^{[19
]}

Yuksel, Aycan ^{[20
]}

Ates, Gungor ^{[21
]}

Kutsoylu, Oya Eren ^{[22
]}

Kose, Neslihan ^{[23
]}

Kizilirmak, Deniz ^{[24
]}

Keskin, Serdar ^{[6
]}

Gultekin, Okkes ^{[25
]}

Coskun, Nilufer ^{[7
]}

Yilmaz, Emine Serap ^{[26
]}

Uslu, Selen ^{[27
]}

Basyigit, Ilknur ^{[9
]}

Ergan, Begum ^{[28
]}

Deveci, Figen ^{[29
]}

Yakar, Mehmet Nuri ^{[30
]}

Zuhur, Cigdem ^{[31
]}

Sagcan, Gulseren ^{[32
]}

Yuce, Zeynep Ture ^{[33
]}

Kuluozturk, Mutlu ^{[29
]}

Sezgin, Mehmet Emin ^{[6
]}

Sezgin, Esma Nur Aktepe ^{[6
]}

Havlucu, Yavuz ^{[24
]}

Cuhadaroglu, Caglar ^{[32
]}

Kilinc, Oguz ^{[34
]}

Boyaci, Hasim ^{[9
]}

Altunay, Hayriye ^{[6
]}

Akti, Mehmet ^{[6
]}

Dursun, Zehra Bastepe ^{[35
]}

Kalem, Ayse Kaya ^{[10
]}

Isik, Sinem Akkaya ^{[36
]}

机构：

[1] Ondokuz Mayis Univ, Dept Pulm Med, Fac Med, Samsun, Turkey

[2] Istinye Univ, Dept Internal Med & Nephrol, Fac Med, Istanbul, Turkey

[3] Kepez State Hosp, Antalya, Turkey

[4] Yildirim Beyazit Univ, Ankara City Hosp, Dept Intens Care Unit, Ankara, Turkey

[5] Adana City Hosp, Adana, Turkey

[6] Siirt Training & Res Hosp, Siirt, Turkey

[7] Sehit Prof Dr Ilhan Varank Training & Res Hosp, Istanbul, Turkey

[8] Erciyes Univ, Sch Med, Dept Pulm Dis, Kayseri, Turkey

[9] Kocaeli Univ, Sch Med, Dept Pulm Dis, Kocaeli, Turkey

[10] Yildirim Beyazit Univ, Ankara City Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey

[11] Univ Med Sci, Samsun Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Samsun, Turkey

[12] Training & Res Hosp, Dept Pulm Med, Istanbul, Turkey

[13] City Hosp, Adana, Turkey

[14] Cukuroca Univ, Dept Pulm Med, Fac Med, Adana, Turkey

[15] Nisantasi Univ, Operating Room Serv Dept, Maslak Acibadem Hosp, Istanbul, Turkey

[16] Nisantasi Univ, Vocat Sch, Private Acibadem Maslak Hosp, Istanbul, Turkey

[17] Hlth Sci Univ, Erzurum Reg Educ & Res Hosp, Dept Infect Dis & Clin Microbiol, Fac Med, Erzurum, Turkey

[18] Dinar State Hosp, Afyon, Turkey

[19] Duzce Ataturk State Hosp, Duzce, Turkey

[20] Ufuk Univ, Dept Pulm Med, Fac Med, Ankara, Turkey

[21] Genesis Private Hosp, Diyarbakir, Turkey

[22] Dokuz Eylul Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Izmir, Turkey

[23] Bilecik State Hosp, Bilecik, Turkey

[24] Celal Bayar Univ, Dept Pulm Med, Fac Med, Manisa, Turkey

[25] Oltu State Hosp, Erzurum, Turkey

[26] Ordu Univ, Training & Res Hosp, Med Fac, Dept Pulm Med, Ordu, Turkey

[27] Ordu Univ, Training & Res Hosp, Med Fac, Dept Pulm Med, Ordu, Turkey

[28] Dokuz Eylul Univ, Div Intens Care, Dept Pulm & Crit Care, Fac Med, Izmir, Turkey

[29] Firat Univ, Dept Pulm Med, Fac Med, Elazig, Turkey

[30] Dokuz Eylul Univ, Div Intens Care, Dept Anaesthesiol & Reanimat, Fac Med, Izmir, Turkey

[31] Private Gelisim Hosp, Iskenderun, Turkey

[32] Private Altunizade Maslak Hosp, Istanbul, Turkey

[33] Erciyes Univ, Dept Infect Dis & Clin Microbiol, Kayseri, Turkey

[34] Dokuz Eylul Univ, Dept Pulm Med, Fac Med, Izmir, Turkey

[35] Hlth Sci Univ, Kayseri City Hosp, Dept Infect Dis & Clin Microbiol, Kayseri, Turkey

[36] Sultan Abdulhamid Han Training & Res Hosp, Istanbul, Turkey

[37] Private Mem Hosp, Diyarbakir, Turkey

[38] Akad Hosp, Istanbul, Turkey

[39] Gazi Univ, Dept Pulm Med, Fac Med, Ankara, Turkey

[40] Dokuz Eylul Univ, Dept Pulm Med, Fac Med, Izmir, Turkey

[41] Ondokuz Mayis Univ Gogus Hst, TR-55139 Samsun, Turkey

来源：

INFECTION | 2022年 / 50卷 / 03期

关键词：

COVID-19; pandemic; vaccine; SinoVac; BioNTech;

D O I：

10.1007/s15010-021-01751-1

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Objective Vaccination is the most efficient way to control the coronavirus disease 2019 (COVID-19) pandemic, but vaccination rates remain below the target level in most countries. This multicenter study aimed to evaluate the vaccination status of hospitalized patients and compare two different booster vaccine protocols. Setting Inoculation in Turkey began in mid-January 2021. Sinovac was the only available vaccine until April 2021, when BioNTech was added. At the beginning of July 2021, the government offered a third booster dose to healthcare workers and people aged > 50 years who had received the two doses of Sinovac. Of the participants who received a booster, most chose BioNTech as the third dose. Methods We collected data from 25 hospitals in 16 cities. Patients hospitalized between August 1 and 10, 2021, were included and categorized into eight groups according to their vaccination status. Results We identified 1401 patients, of which 529 (37.7%) were admitted to intensive care units. Nearly half (47.8%) of the patients were not vaccinated, and those with two doses of Sinovac formed the second largest group (32.9%). Hospitalizations were lower in the group which received 2 doses of Sinovac and a booster dose of BioNTech than in the group which received 3 doses of Sinovac. Conclusion Effective vaccinations decreased COVID-19-related hospitalizations. The efficacy after two doses of Sinovac may decrease over time; however, it may be enhanced by adding a booster dose. Moreover, unvaccinated patients may be persuaded to undergo vaccination.

引用

页码：747 / 752

页数：6

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