Spermatogonial Stem Cell Culture in Oncofertility

被引:17
|
作者
David, Sherin [1 ]
Orwig, Kyle E. [1 ]
机构
[1] Univ Pittsburgh, Magee Womens Res Inst, Dept Obstet Gynecol & Reprod Sci, Mol Genet & Dev Biol Grad Program,Sch Med, 204 Craft Ave, Pittsburgh, PA 15213 USA
关键词
Spermatogonial stem cell culture; Fertility preservation; Male fertility; TESTICULAR TISSUE CRYOPRESERVATION; LONG-TERM PROLIFERATION; IN-VITRO; GERM-CELLS; FERTILITY PRESERVATION; SELF-RENEWAL; HUMAN TESTIS; NONOBSTRUCTIVE AZOOSPERMIA; OVARIAN TISSUE; MOUSE TESTIS;
D O I
10.1016/j.ucl.2020.01.001
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Infertility caused by chemotherapy or radiation treatments negatively impacts patient-survivor quality of life. The only fertility preservation option available to prepubertal boys who are not making sperm is cryopreservation of testicular tissues that contain spermatogonial stem cells (SSCs) with potential to produce sperm and/or restore fertility. SSC transplantation to regenerate spermatogenesis in infertile adult survivors of childhood cancers is a mature technology. However, the number of SSCs obtained in a biopsy of a prepubertal testis may be small. Therefore, methods to expand SSC numbers in culture before transplantation are needed. Here we review progress with human SSC culture.
引用
收藏
页码:227 / +
页数:19
相关论文
共 50 条
  • [1] Review of injection techniques for spermatogonial stem cell transplantation
    Gul, Murat
    Hildorf, Simone
    Dong, Lihua
    Thorup, Jorgen
    Hoffmann, Eva R.
    Jensen, Christian Fuglesang S.
    Sonksen, Jens
    Cortes, Dina
    Fedder, Jens
    Andersen, Claus Yding
    Goossens, Ellen
    HUMAN REPRODUCTION UPDATE, 2020, 26 (03) : 368 - 391
  • [2] Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions
    Medrano, Jose V.
    Rombaut, Charlotte
    Simon, Carlos
    Pellicer, Antonio
    Goossens, Ellen
    FERTILITY AND STERILITY, 2016, 106 (06) : 1539 - +
  • [3] Spermatogonial Stem Cell-Based Therapies: Taking Preclinical Research to the Next Level
    Sanou, Iris
    van Maaren, Jillis
    Eliveld, Jitske
    Lei, Qijing
    Meissner, Andreas
    de Melker, Annemieke A.
    Hamer, Geert
    van Pelt, Ans M. M.
    Mulder, Callista L.
    FRONTIERS IN ENDOCRINOLOGY, 2022, 13
  • [4] Culture and transplantation of spermatogonial stem cells
    Takashima, Seiji
    Shinohara, Takashi
    STEM CELL RESEARCH, 2018, 29 : 46 - 55
  • [5] Quantitative detection of human spermatogonia for optimization of spermatogonial stem cell culture
    Zheng, Y.
    Thomas, A.
    Schmidt, C. M.
    Dann, C. T.
    HUMAN REPRODUCTION, 2014, 29 (11) : 2497 - 2511
  • [6] The Spermatogonial Stem Cell Niche
    De Rooij, Dirk G.
    MICROSCOPY RESEARCH AND TECHNIQUE, 2009, 72 (08) : 580 - 585
  • [7] Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
    Nobrega, Rafael Henrique
    Greebe, Caaj Douwe
    van de Kant, Henk
    Bogerd, Jan
    de Franca, Luiz Renato
    Schulz, Rudiger W.
    PLOS ONE, 2010, 5 (09): : 1 - 16
  • [8] Timing of spermatogonial stem cell transplantation affects the spermatogenic recovery outcome in mice
    Medrano, J. V.
    Acimovic, I.
    Navarro-Gomezlechon, A.
    Noguera, I.
    Pellicer, A.
    Andres, M. M.
    Novella-Maestre, E.
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2021, 57 (01) : 21 - 29
  • [9] Future of Spermatogonial Stem Cell Culture: Application of Nanofiber Scaffolds
    Shams, Azar
    Eslahi, Neda
    Movahedin, Mansoureh
    Izadyar, Fariborz
    Asgari, Hamidreza
    Koruji, Morteza
    CURRENT STEM CELL RESEARCH & THERAPY, 2017, 12 (07) : 544 - 553
  • [10] Reconstitution of Mouse Spermatogonial Stem Cell Niches in Culture
    Kanatsu-Shinohara, Mito
    Inoue, Kimiko
    Takashima, Seiji
    Takehashi, Masanori
    Ogonuki, Narumi
    Morimoto, Hiroko
    Nagasawa, Takashi
    Ogura, Atsuo
    Shinohara, Takashi
    CELL STEM CELL, 2012, 11 (04) : 567 - 578