A novel and efficient method combining SFE and liquid-liquid extraction for separation of coumarins from Angelica dahurica

被引：23
作者：
Wang, Long-Hu [1 ]
Mei, Yan-Hong [1 ]
Wang, Feng [1 ]
Liu, Xue-Song [1 ]
Chen, Yong [1 ]
机构：
[1] Zhejiang Univ, Dept Chinese Med Sci & Engn, Hangzhou 310058, Zhejiang, Peoples R China
来源：
SEPARATION AND PURIFICATION TECHNOLOGY | 2011年 / 77卷 / 03期
关键词：
Angelica dahurica; Coumarins; Supercritical fluid extraction; SFE; LLE; SUPERCRITICAL-FLUID EXTRACTION; IDENTIFICATION; CHROMATOGRAPHY; OXYPEUCEDANIN; IMPERATORIN;
D O I：
10.1016/j.seppur.2010.12.020
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Nowadays supercritical fluid extraction (SFE) as an alternative is popular in food and pharmaceutical industries but its large scale application is often restricted economically by the confliction between recovery efficiency and selectivity. In this article, a simple but novel and efficient combined method was investigated for separating coumarins from Angelica dahurica. The experimental results showed that combining SFE and liquid-liquid extraction could improve both extraction selectivity and separation efficiency, enriching easily coumarins from 0.144% in the herb to as much as 41.68% in the concentrate. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：397 / 401
页数：5
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