Acute liver failure in children

被引：39

作者：

Devictor, Denis ^{[1
]}

Tissieres, Pierre ^{[1
]}

Afanetti, Mickael ^{[1
]}

Debray, Dominique ^{[2
]}

机构：

[1] Univ Paris 11, Bicetre Hosp, AP HP, Pediat Intens Care Unit,Dept Pediat, F-94275 Le Kremlin Bicetre, France

[2] Necker Enfants Malades Hosp, AP HP, F-75015 Paris, France

来源：

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY | 2011年 / 35卷 / 6-7期

关键词：

FULMINANT HEPATIC-FAILURE; INTRACRANIAL HYPERTENSION; HEPATORENAL-SYNDROME; CEREBRAL PERFUSION; TRANSPLANTATION; EXPERIENCE; PATHOGENESIS; PRESSURE; SURVIVAL; INFANTS;

D O I：

10.1016/j.clinre.2011.03.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The management of children with acute liver failure mandates a multidisciplinary approach and intense monitoring. In recent years, considerable progress has been made in developing specific and supportive medical measures, but clinical studies have mainly concerned adult patients. There are no specific medical therapies, except for a few metabolic diseases presenting with acute liver failure. Liver transplantation still remains the only definitive therapy in most instances. Recent clinical studies suggest that hepatocyte transplantation may be useful for bridging patients to liver transplantation, for providing metabolic support during liver failure and for replacing liver transplantation in certain metabolic liver diseases. (C) 2011 Published by Elsevier Masson SAS.

引用

页码：430 / 437

页数：8

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