1,3-Dipolar Cycloaddition on Baylis-Hillman Adducts: Novel Synthesis of Pyrrolidines, Spiropyrrolidines, and Spiropyrrolizidines

被引：23
作者：
Bakthadoss, Manickam [1 ]
Sivakumar, Nagappan [1 ]
Devaraj, Anthonisamy [1 ]
Sharada, Duddu S. [2 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
[2] Cent Leather Res Inst, Div Organ Chem, Madras 600020, Tamil Nadu, India
来源：
SYNTHESIS-STUTTGART | 2011年 / 13期
关键词：
Baylis-Hillman reaction; intermolecular [3+2] cycloaddition; azomethine ylides; 1,3-dipolar cycloaddition; pyrrolidines; spiro compounds; CELL CYCLE INHIBITORS; AZOMETHINE YLIDES; STEREOSELECTIVE-SYNTHESIS; REDUCTIVE CYCLIZATION; ASPERGILLUS-FUMIGATUS; EFFICIENT SYNTHESIS; OXINDOLE ALKALOIDS; NITRILE OXIDES; DERIVATIVES; CHEMISTRY;
D O I：
10.1055/s-0030-1260053
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile regio- and stereoselective synthesis of functionalized pyrrolidines, spiropyrrolidines, and spiropyrrolizidines using the Baylis-Hillman adducts derived from nitroolefins via intermolecular [3+2]-cycloaddition reaction is reported.
引用
收藏
页码：2136 / 2146
页数：11
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