The Effect of Preoperative Portal Vein Embolization on Liver Regeneration after Extended Hepatic Resection

被引：0
|
作者：
Kim, Sung Hoon [1 ]
Kim, Im Kyung [1 ]
Hong, Young Ki [4 ]
Chol, Sae Byeol [5 ]
Lee, Kwang Hun [2 ]
Park, Seung Woo [3 ]
Kim, Kyung Sik [1 ]
机构：
[1] Yonsei Univ, Coll Med, Dept Surg, Seoul 120752, South Korea
[2] Yonsei Univ, Coll Med, Dept Radiol, Seoul 120752, South Korea
[3] Yonsei Univ, Coll Med, Dept Internal Med, Seoul 120752, South Korea
[4] Natl Hlth Insurance Ilsan Hosp, Dept Surg, Koyang, Kyunggi Do, South Korea
[5] Korea Univ, Coll Med, Dept Surg, Seoul 136705, South Korea
来源：
HEPATO-GASTROENTEROLOGY | 2011年 / 58卷 / 106期
关键词：
TRANSFORMING GROWTH-FACTOR; HEPATOCELLULAR-CARCINOMA; HILAR CHOLANGIOCARCINOMA; ARTERIAL EMBOLIZATION; DNA-SYNTHESIS; HEPATECTOMY; RAT; ALPHA; INDUCTION; LIGATION;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background/Aims: This study was designed to evaluate the effect of portal vein embolization on liver regeneration after major liver resection. Methodology: A retrospective analysis was performed on 24 patients who underwent extended hepatectomy for hilar cholangicellular carcinoma between 2001 and 2008. Eleven patients underwent portal vein embolization and 13 did not. Computed tomography volumetry was used to assess liver volume. Results: Clinical and operative characteristics were comparable between portal vein embolization group and non-portal vein embolization group, except for mean estimated blood loss (p=0.034). Future remnant liver volume (p=0.004) differed between groups. However, preoperative future remnant liver volume (p=0.331), postoperative mean volume of the left lateral segement (p>0.9), total volume increase (p>0.9), and daily volume increase (p>0.9) did not differ significantly between groups. Within the portal vein embolization group, mean volume of the left lateral segment and daily volume increase after hepatic resection were significantly greater than after portal vein embolization (p=0.002). Conclusion: Liver regeneration after portal vein embolization was insignificant in comparison with that after extended hepatectomy. Moreover, portal vein embolization performed before extended hepatectomy did not reinforce liver regeneration after major liver resection.
引用
收藏
页码：516 / 521
页数：6
相关论文
共 50 条
  • [41] Preoperative portal vein or portal and hepatic vein embolization: DRAGON collaborative group analysis
    Heil, J.
    Korenblik, R.
    Heid, F.
    Bechstein, W. O.
    Bemelmans, M.
    Binkert, C.
    Bjornsson, B.
    Breitenstein, S.
    Detry, O.
    Dili, A.
    Dondelinger, R. F.
    Gerard, L.
    Gimenez-Maurel, T.
    Guiu, B.
    Heise, D.
    Hertl, M.
    Kalil, J. A.
    Klein, J. J.
    Lakoma, A.
    Neumann, U. P.
    Olij, B.
    Pappas, S. G.
    Sandstrom, P.
    Schnitzbauer, A.
    Serrablo, A.
    Tasse, J.
    Van der Leij, C.
    Metrakos, P.
    Van Dam, R.
    Schadde, E.
    BRITISH JOURNAL OF SURGERY, 2021, 108 (07) : 834 - 842
  • [42] Laparoscopic Right Hepatectomy Extended to Middle Hepatic Vein After Right Portal Vein Embolization
    Rotellar, Fernando
    Pardo, Fernando
    Benito, Alberto
    Marti-Cruchaga, Pablo
    Zozaya, Gabriel
    Bellver, Manuel
    ANNALS OF SURGICAL ONCOLOGY, 2014, 21 (01) : 165 - 166
  • [43] Laparoscopic Right Hepatectomy Extended to Middle Hepatic Vein After Right Portal Vein Embolization
    Fernando Rotellar
    Fernando Pardo
    Alberto Benito
    Pablo Martí-Cruchaga
    Gabriel Zozaya
    Manuel Bellver
    Annals of Surgical Oncology, 2014, 21 : 165 - 166
  • [44] Successful Thrombectomy via a Surgically Reopened Umbilical Vein for Extended Portal Vein Thrombosis Caused by Portal Vein Embolization prior to Extended Liver Resection
    Derksen, WouterJ. M.
    deJong, Iris E. M.
    Buis, CarlijnI.
    Reyntjens, KoenM. E. M.
    Kater, G. Matthijs
    Korteweg, Tijmen
    Mazuri, Aryan
    Porte, RobertJ.
    CASE REPORTS IN GASTROENTEROLOGY, 2020, 14 (02) : 320 - 328
  • [45] Impaired liver function attenuates liver regeneration and hypertrophy after portal vein embolization
    Yumiko Kageyama
    Takashi Kokudo
    Katsumi Amikura
    Yoshihiro Miyazaki
    Amane Takahashi
    Hirohiko Sakamoto
    World Journal of Hepatology, 2016, (28) : 1200 - 1204
  • [46] Portal vein embolization preparation for major hepatic resection: A new standard in liver surgery
    Uhl, M.
    Euringer, W.
    Makowiec, F.
    Adam, U.
    Schneider, A.
    Langer, M.
    ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2007, 179 (01): : 31 - 35
  • [47] Impaired liver function attenuates liver regeneration and hypertrophy after portal vein embolization
    Kageyama, Yumiko
    Kokudo, Takashi
    Amikura, Katsumi
    Miyazaki, Yoshihiro
    Takahashi, Amane
    Sakamoto, Hirohiko
    WORLD JOURNAL OF HEPATOLOGY, 2016, 8 (28) : 1200 - 1204
  • [48] Prediction of the Remnant Liver Hypertrophy Ratio after Preoperative Portal Vein Embolization
    Kasai, Y.
    Hatano, E.
    Iguchi, K.
    Seo, S.
    Taura, K.
    Yasuchika, K.
    Mori, A.
    Kaido, T.
    Tanaka, S.
    Shibata, T.
    Shibata, T.
    Uemoto, S.
    EUROPEAN SURGICAL RESEARCH, 2013, 51 (3-4) : 129 - 137
  • [49] Increase in future remnant liver function after preoperative portal vein embolization
    de Graaf, W.
    van Lienden, K. P.
    van den Esschert, J. W.
    Bennink, R. J.
    van Gulik, T. M.
    BRITISH JOURNAL OF SURGERY, 2011, 98 (06) : 825 - 834
  • [50] Combined preoperative embolization of the right portal vein and hepatic artery for hepatic resection in a high-risk patient
    Takada, T
    Ammori, BJ
    Yoshida, M
    Amano, H
    Yasuda, H
    Takeshita, K
    Koutake, H
    Takada, K
    Miyakawa, S
    AMERICAN JOURNAL OF ROENTGENOLOGY, 1999, 173 (01) : 165 - 167
12345