An improved method of ring closing metathesis in the presence of basic amines: application to the formal synthesis of (+)-lentiginosine and other piperidines and carbamino sugar analogs

被引：26

作者：

Lahiri, Rima ^{[1
]}

Kokatla, Hari Prasad ^{[1
]}

Vankar, Yashwant D. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 07期

关键词：

Metathesis; Basic amines; Azasugars; Lentiginosine; OLEFIN METATHESIS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; IMINO SUGARS; 1-DEOXYNOJIRIMYCIN ANALOGS; STEREOSELECTIVE-SYNTHESIS; GLUCOSIDASE INHIBITOR; D-GALACTOSE; HETEROCYCLES; ROUTE;

D O I：

10.1016/j.tetlet.2010.12.020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A generalized method for performing ring closing metathesis in the presence of basic amines has been established and successfully used in the formal synthesis of (+)-lentiginosine as well as some valuable intermediates for the synthesis of several other azasugars and aminocyclitols. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：781 / 786

页数：6

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